SCHEMBL369646

SCHEMBL369646

C=CCc1ccccc1COC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
KDM4E B2RXH2 3/20 0.40
MAPT P10636 1/20 0.40
THRB P10828 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HTR1A P08908 2/20 0.39
ADRA2C P18825 2/20 0.39
ADRA2A P08913 1/20 0.39
ADRA2B P18089 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
ADRB2 P07550 3/20 0.38
ADRB1 P08588 3/20 0.38
LMNA P02545 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL939841 0.83 GABRA1 (0.45) GABRA1GABRB2KDM4EMAPTTHRB
SCHEMBL8680424 0.83 GABRA1 (0.45) GABRA1GABRB2KDM4EMAPTTHRB
SCHEMBL29763626 0.82 GABRA1 (0.56) GABRA1GABRB2KDM4EMAPTALDH1A1
SCHEMBL648491 0.82 IDO1 (0.44) KDM4EMAPTALDH1A1TSHRALOX12
SCHEMBL173300 0.82 GABRA1 (0.56) GABRA1GABRB2KDM4EMAPTALDH1A1
SCHEMBL18657301 0.81 GABRA1 (0.59) GABRA1GABRB2KDM4EMAPTALDH1A1
Phosphine SCHEMBL28908229 0.79 GABRA1 (0.54) GABRA1GABRB2KDM4EMAPTALDH1A1
SCHEMBL19437729 0.79 GABRA1 (0.54) GABRA1GABRB2KDM4EMAPTALDH1A1
SCHEMBL10528834 0.79 GABRA1 (0.54) GABRA1GABRB2KDM4EMAPTALDH1A1
Benzene SCHEMBL28085432 0.79 GABRA1 (0.54) GABRA1GABRB2KDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8889920-B2 Process for preparing 4-isopropylcyclohexylmethanol BASF SE (DE) 2014-11-18 US disclosed
US-8629304-B2 Electrochemical method for producing 3-tert-butylbenzaldehyde dimethyl acetal BASF SE (DE) 2014-01-14 US disclosed
US-20120016162-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3-TERT-BUTYLBENZALDEHYDE DIMETHYL ACETAL BASF SE (DE) 2012-01-19 US disclosed
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL BASF SE (DE) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110207968-A1 PROCESS FOR PREPARING 4-ISOPROPYLCYCLOHEXYLMETHANOL CYP2E1, CYP3A4, DHPS GABRA1 3620/4885GABRB2 2756/4885KDM4E 89/4885
US-20120016162-A1 ELECTROCHEMICAL METHOD FOR PRODUCING 3-TERT-BUTYLBENZALDEHYDE DIMETHYL ACETAL TET3, TERT, ALKBH2 GABRA1 2453/4885GABRB2 897/4885KDM4E 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.