Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704211 | 0.90 | SMN1; SMN2 (0.44) | KDM4EALDH1A1SMN1; SMN2PKMCYP1A2 | |
| SCHEMBL3699318 | 0.87 | MAPT (0.42) | KDM4EALDH1A1SMN1; SMN2PKMCYP1A2 | |
| SCHEMBL9102425 | 0.86 | MAPT (0.44) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9107398 | 0.86 | KMT2A (0.40) | KDM4EALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9102458 | 0.83 | MAPT (0.42) | KDM4EALDH1A1POLBMAPTLMNA | |
| SCHEMBL3704087 | 0.82 | TAAR1 (0.44) | KDM4EALDH1A1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL9103931 | 0.82 | ITGB2 (0.44) | ALDH1A1SMN1; SMN2PKMCYP1A2CYP3A4 | |
| SCHEMBL3700824 | 0.82 | ITGB2 (0.37) | KDM4EALDH1A1SMN1; SMN2PKMCYP1A2 | |
| SCHEMBL3698675 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP3A4MAPTLMNA | |
| SCHEMBL9105229 | 0.82 | ITGB2 (0.39) | KDM4EALDH1A1SMN1; SMN2PKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040701-B2 | Apaf-1 inhibitor compounds | LABORATORIOS SALVAT, S.A. (ES) | 2015-05-26 | — | — | US | disclosed |
| EP-2460798-A2 | APAF-1 INHIBITOR COMPOUNDS | Laboratorios SALVAT, S.A. (ES) | 2012-06-06 | — | — | EP | disclosed |
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | LABORATORIOS SALVAT, S.A. (ES) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122868-A1 | APAF-1 INHIBITOR COMPOUNDS | APAF1, API5, AIFM1 | KDM4E 3196/4885ALDH1A1 701/4885SMN1; SMN2 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.