Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGFR | P43088 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL3685075 | 0.98 | NFKB1 (0.43) | NFKB1GPR84FFAR4FFAR1TBXA2R | |
| SCHEMBL3695705 | 0.98 | NFKB1 (0.43) | NFKB1GPR84FFAR4FFAR1TBXA2R | |
| Zinc Ion SCHEMBL3696414 | 0.98 | NFKB1 (0.43) | NFKB1GPR84FFAR4FFAR1TBXA2R | |
| SCHEMBL3688984 | 0.98 | NFKB1 (0.45) | NFKB1GPR84FFAR4FFAR1TBXA2R | |
| Stearic Acid SCHEMBL3691279 | 0.94 | GNAI3 (0.40) | GNAI3GNAO1GNAI1CA12CA9 | |
| Stearic Acid SCHEMBL3694355 | 0.92 | CA12 (0.38) | GNAI3GNAO1GNAI1CA12CA9 | |
| Stearic Acid SCHEMBL3692578 | 0.92 | CA12 (0.38) | GNAI3GNAO1GNAI1CA12CA9 | |
| Stearic Acid SCHEMBL3692455 | 0.92 | CA12 (0.38) | GNAI3GNAO1GNAI1CA12CA9 | |
| Stearic Acid SCHEMBL3695324 | 0.92 | CA12 (0.38) | GNAI3GNAO1GNAI1CA12CA9 | |
| SCHEMBL3689865 | 0.88 | NFKB1 (0.46) | NFKB1GPR84FFAR4FFAR1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723413-B2 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-20070142514-A1 | Method and composition for control of crystallization rate of polyolefin resin, resin composition and resin molding | NEW JAPAN CHEMICAL CO., LTD. (JP) | 2007-06-21 | — | — | US | disclosed |