Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.31 |
| ▸ | HTR3B | O95264 | 3/20 | 0.31 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32687961 | 0.84 | KDM4E (0.32) | ALDH1A1KDM4EHSD17B10CYP1A2HPGD | |
| SCHEMBL16403224 | 0.67 | KDM4E (0.40) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL30602270 | 0.65 | TDP1 (0.39) | HTR3ASLC6A4TDP1HRH3 | |
| SCHEMBL9203182 | 0.61 | HRH1 (0.52) | CASP1CASP4CASP5HRH4ALDH1A1 | |
| SCHEMBL1880450 | 0.61 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10HPGDPOLB | |
| SCHEMBL4421139 | 0.61 | ADRB2 (0.36) | BPTFPLD1CASP1CASP4CASP5 | |
| SCHEMBL15057332 | 0.60 | — | — | |
| SCHEMBL4418585 | 0.60 | ADRB2 (0.35) | BPTFPLD1CASP1CASP4CASP5 | |
| SCHEMBL13536713 | 0.60 | ADRB2 (0.40) | PLD1CASP1CASP4CASP5HRH4 | |
| SCHEMBL4554180 | 0.60 | ALDH1A1 (0.36) | CASP1ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009934-A1 | BETA ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009934-A1 | BETA ADRENERGIC RECEPTOR AGONISTS FOR THE TREATMENT OF B-CELL PROLIFERATIVE DISORDERS | ADRB1, ADRB2, ADRA2B | BPTF 1120/4885PLD1 521/4885CASP1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.