SCHEMBL369819

SCHEMBL369819

CCOC(=O)Oc1ncn(-c2cccnc2)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 2/20 0.41
NPEPPS P55786 1/20 0.41
CYP2E1 P05181 2/20 0.40
CYP2A6 P11509 2/20 0.40
CYP3A4 P08684 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
ELANE P08246 1/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
LMNA P02545 3/20 0.40
MAPK1 P28482 2/20 0.39
TSHR P16473 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
CCNC P24863 1/20 0.39
CDK8 P49336 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2113181 0.80 GABRA5 (0.49) KMT2AALDH1A1MEN1CYP2E1CYP2A6
SCHEMBL9372775 0.77 CYP2A6 (0.53) KMT2AALDH1A1MEN1NPEPPSCYP2E1
SCHEMBL369853 0.74 NPC1 (0.44) KMT2AALDH1A1MEN1NPEPPSNPC1
SCHEMBL9521880 0.72 CCNC (0.58) KMT2AALDH1A1MEN1NPC1RAB9A
Hydrochloric Acid SCHEMBL9839090 0.71 CCNC (0.57) KMT2AALDH1A1MEN1NPC1RAB9A
SCHEMBL9373433 0.68 NOTUM (0.59) KMT2AALDH1A1MEN1CYP2E1CYP2A6
SCHEMBL7603908 0.68 L3MBTL1 (0.43) ALDH1A1CYP3A4NPC1RAB9ALMNA
SCHEMBL6186021 0.67 ALDH1A1 (0.50) ALDH1A1CYP3A4NPC1RAB9ALMNA
SCHEMBL7176953 0.66 KCNH2 (0.54) NPC1RAB9AELANE
SCHEMBL31456637 0.66 NPC1 (0.54) KMT2AALDH1A1MEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2593447-A2 NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES Bayer Intellectual Property GmbH (DE) 2013-05-22 EP disclosed
WO-2012007500-A2 NEW HETEROCYCLIC COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2012-01-19 WO disclosed