Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 2/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | TXN | P10599 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.39 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.39 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29770413 | 1.00 | CACNA1G (0.49) | CACNA1GCACNA1HRIPK1GAAHTT | |
| SCHEMBL13804780 | 0.88 | CACNA1H (0.51) | CACNA1GCACNA1HGAAHTTPRKAG1 | |
| SCHEMBL5242659 | 0.75 | NPSR1 (0.51) | RAB9AEGLN1MEN1KMT2A | |
| SCHEMBL13141653 | 0.75 | NPC1 (0.56) | CACNA1GCACNA1HPRSS12RAB9AMEN1 | |
| SCHEMBL27241025 | 0.74 | GAA (0.57) | CACNA1GCACNA1HGAAHTTPRKAG1 | |
| SCHEMBL7208984 | 0.73 | RIPK1 (0.58) | CACNA1GCACNA1HRIPK1GAAHTT | |
| SCHEMBL1440520 | 0.71 | GAA (0.55) | GAAPRSS12 | |
| SCHEMBL3699142 | 0.71 | CYP1A2 (0.43) | RIPK1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL29770407 | 0.71 | RAF1 (0.48) | RIPK1PRSS12CYP1A2RAB9AMEN1 | |
| SCHEMBL5364367 | 0.71 | RIPK1 (0.44) | RIPK1CAMK2DKCNN1KCNN2KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132479-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132479-A1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | CUTA, DCXR, PLOD3 | CACNA1G 4475/4885CACNA1H 4365/4885RIPK1 2558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.