Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3690164 | 0.87 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL1583743 | 0.76 | CFTR (0.53) | ALDH1A1PKMPOLBHPGDMEN1 | |
| SCHEMBL17595049 | 0.71 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL1583694 | 0.70 | KDM4E (0.41) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL3063932 | 0.70 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1POLBHPGDADORA2B | |
| SCHEMBL3803196 | 0.68 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL9219906 | 0.68 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL3699787 | 0.68 | PKM (0.38) | ALDH1A1PKMPOLBHPGDMEN1 | |
| SCHEMBL19194844 | 0.67 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1PKMPOLBHPGD | |
| SCHEMBL1583944 | 0.67 | RXFP1 (0.41) | L3MBTL1ALDH1A1PKMKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | GLAXOSMITHKLINE LLC | 2012-05-17 | — | — | US | disclosed |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | GLAXOSMITHKLINE LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | OAT, HAVCR2, CPS1 | L3MBTL1 3542/4885ALDH1A1 1337/4885PKM 2286/4885 |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | OAT, HAVCR2, CPS1 | L3MBTL1 3542/4885ALDH1A1 1337/4885PKM 2286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.