Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 4/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583743 | 0.85 | CFTR (0.53) | PKMRXFP1CFTRALDH1A1KDM4E | |
| SCHEMBL1583694 | 0.82 | KDM4E (0.41) | PKMRXFP1CFTRALDH1A1KDM4E | |
| SCHEMBL3699785 | 0.82 | ADORA3 (0.39) | PKMRXFP1CFTRALDH1A1KDM4E | |
| SCHEMBL3690164 | 0.81 | ALDH1A1 (0.47) | PKMCFTRALDH1A1KDM4EPOLB | |
| SCHEMBL3696233 | 0.80 | PKM (0.49) | PKMRXFP1ALDH1A1KDM4EPOLB | |
| SCHEMBL3684339 | 0.79 | ALDH1A1 (0.48) | PKMRXFP1ALDH1A1KDM4EPOLB | |
| SCHEMBL3703771 | 0.78 | SCD5 (0.47) | PKMRXFP1ADORA3SCD5CYP2C8 | |
| SCHEMBL7490436 | 0.77 | ALDH1A1 (0.48) | PKMRXFP1ALDH1A1KDM4EPOLB | |
| SCHEMBL3702560 | 0.77 | ADORA2A (0.46) | PKMRXFP1ALDH1A1ADORA3RAB9A | |
| SCHEMBL7495802 | 0.77 | CACNA1B (0.48) | PKMRXFP1ALDH1A1KDM4ESCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | GLAXOSMITHKLINE LLC | 2012-05-17 | — | — | US | disclosed |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | GLAXOSMITHKLINE LLC | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120121540-A1 | Certain Nitrogen Containing Bicyclic Chemical Entities For Treating Viral Infections | OAT, HAVCR2, CPS1 | PKM 2286/4885RXFP1 4676/4885CFTR 2042/4885 |
| US-20090176778-A1 | Certain nitrogen containing bicyclic chemical entities for treating viral infections | OAT, HAVCR2, CPS1 | PKM 2286/4885RXFP1 4676/4885CFTR 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.