SCHEMBL580565

SCHEMBL580565

COc1cc(OC)c(OC)cc1Br

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PRKDC P78527 1/20 0.54
HTR2A P28223 7/20 0.54
TAAR1 Q96RJ0 3/20 0.54
HTR2C P28335 2/20 0.54
LCK P06239 1/20 0.52
FYN P06241 1/20 0.52
MAPT P10636 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GRIN2D O15399 1/20 0.50
GRIN3B O60391 1/20 0.50
GRIN1 Q05586 1/20 0.50
GRIN2A Q12879 1/20 0.50
GRIN2B Q13224 1/20 0.50
GRIN2C Q14957 1/20 0.50
GRIN3A Q8TCU5 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30202128 1.00 POLB (0.54) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL298224 0.94 POLB (0.59) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL1104878 0.91 GRIN2D (0.52) POLBL3MBTL1HTR2ATAAR1HTR2C
SCHEMBL13517864 0.89 L3MBTL1 (0.50) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL28799442 0.88 POLB (0.61) POLBL3MBTL1HTR2ATAAR1HTR2C
SCHEMBL29878552 0.88 POLB (0.67) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL369991 0.88 POLB (0.67) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL5050153 0.86 POLB (0.52) POLBL3MBTL1HTR2ATAAR1HTR2C
SCHEMBL27143368 0.86 POLB (0.52) POLBL3MBTL1PRKDCHTR2ATAAR1
SCHEMBL21757392 0.84 LMNA (0.52) HTR2ATAAR1HTR2CMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113387804-B Synthesis method of alpha-asarone acetate and alpha-octanol 西安石油大学 2023-05-02 CN claimed
CN-113387804-A Synthetic method of acetic acid alpha-asaryl alcohol ester and alpha-fine octanol 西安石油大学 2021-09-14 CN claimed
US-20250288553-A1 Antimicrobial Compositions and Uses for Treatment of Clostridioides difficile, Mycobacterium tuberculosis, and Enterococcus faecalis Infection THE UNIVERSITY OF TOLEDO 2025-09-18 US disclosed
US-12275711-B2 Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) 2025-04-15 US disclosed
WO-2023215619-A2 ANTIMICROBIAL COMPOSITIONS AND USES FOR TREATMENT OF CLOSTRIDIOIDES DIFFICILE, MYCOBACTERIUM TUBERCULOSIS, AND ENTEROCOCCUS FAECALIS INFECTION UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-09 WO disclosed
CN-116836148-A Method for co-production of organic bromide and hydrogen through photocatalysis 中国科学院大连化学物理研究所 2023-10-03 CN disclosed
CN-113387804-B Synthesis method of alpha-asarone acetate and alpha-octanol 西安石油大学 2023-05-02 CN disclosed
US-20220144785-A1 COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG (ZA) 2022-05-12 US disclosed
EP-3938355-A1 COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE University Of The Witwatersrand, Johannesburg (ZA) 2022-01-19 EP disclosed
CN-113692403-A Compounds with Excited State Intramolecular Proton Transfer (ESIPT) properties for use in the treatment and/or prevention of sunburn and/or prevention of U.V. damage 约翰内斯堡威特沃特斯兰德大学 2021-11-23 CN disclosed
CN-113387804-A Synthetic method of acetic acid alpha-asaryl alcohol ester and alpha-fine octanol 西安石油大学 2021-09-14 CN disclosed
CN-101166706-B Hydroquinone long-chain derivative and/or phenoxy long-chain derivative, and pharmaceutical preparation comprising the same MEIJI MILK PROD CO LTD 2011-08-24 CN disclosed
WO-2011034071-A1 PROCESS FOR PRODUCTION OF OXIDATION REACTION PRODUCT OF AROMATIC COMPOUND 国立大学法人大阪大学 (JP) 2011-03-24 WO disclosed
US-7893304-B2 Hydroquinone long-chain derivatives and/or phenoxy long-chain derivatives, and pharmaceuticals comprising the same MEIJI DAIRIES CORPORATION (JP) 2011-02-22 US disclosed
US-20090036542-A1 Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2009-02-05 US disclosed
CN-101166706-A Hydroquinone long-chain derivative and/or phenoxy long-chain derivative, and pharmaceutical preparation comprising the same MEIJI DAIRIES CORP (JP) 2008-04-23 CN disclosed
EP-1854777-A1 HYDROQUINONE LONG-CHAIN DERIVATIVE AND/OR PHENOXY LONG-CHAIN DERIVATIVE, AND PHARMACEUTICAL PREPARATION COMPRISING THE SAME Meiji Dairies Corporation (JP) 2007-11-14 EP disclosed
US-6194439-B1 ANTICANCER AGENT PFIZER INC. 2001-02-27 US disclosed
EP-0586608-A1 TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS PFIZER INC. (US) 1994-03-16 EP disclosed
WO-1992021660-A1 TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS PFIZER, INC. (US) 1992-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12275711-B2 Compounds having excited state intramolecular proton transfer (ESIPT) character for use in treating and/or preventing sunburn and/or preventing U.V. damage NNT, NQO1, SUN2 POLB 2283/4885L3MBTL1 747/4885PRKDC 4527/4885
US-20250288553-A1 Antimicrobial Compositions and Uses for Treatment of Clostridioides difficile, Mycobacterium tuberculosis, and Enterococcus faecalis Infection VDR, CYP2R1, PTH1R POLB 1000/4885L3MBTL1 1201/4885PRKDC 2304/4885
US-20090036542-A1 Hydroquinone Long-Chain Derivative and/or Phenoxy Long-Chain Derivative and Pharmaceutical Comprising Same NQO1, NDUFA10, UQCRC1 POLB 2070/4885L3MBTL1 1504/4885PRKDC 4369/4885
US-20220144785-A1 COMPOUNDS HAVING EXCITED STATE INTRAMOLECULAR PROTON TRANSFER (ESIPT) CHARACTER FOR USE IN TREATING AND/OR PREVENTING SUNBURN AND/OR PREVENTING U.V. DAMAGE NNT, NQO1, SUN2 POLB 2283/4885L3MBTL1 747/4885PRKDC 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.