Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707761 | 0.93 | DUSP3 (0.35) | LPAR1LPAR2LPAR3HIF1ACTSA | |
| SCHEMBL3711509 | 0.91 | ACR (0.36) | LPAR1LPAR2LPAR3HIF1AACR | |
| SCHEMBL2335317 | 0.88 | LPAR1 (0.38) | LPAR1LPAR2LPAR3NR1H4KDM4E | |
| SCHEMBL3711048 | 0.85 | ALDH1A1 (0.37) | LPAR1LPAR2LPAR3CTSAACR | |
| SCHEMBL3711407 | 0.85 | ACR (0.36) | HIF1AACRNR1H4L3MBTL1F9 | |
| SCHEMBL2338262 | 0.84 | LPAR1 (0.50) | LPAR1LPAR2LPAR3NR1H4 | |
| SCHEMBL3711161 | 0.84 | LDHA (0.41) | LPAR1LPAR2LPAR3ALOX5ALOX5AP | |
| SCHEMBL3712570 | 0.84 | CYP2C9 (0.36) | LPAR1LPAR2LPAR3CTSANR1H4 | |
| SCHEMBL2332523 | 0.84 | MAPT (0.40) | LPAR1LPAR2LPAR3ACRL3MBTL1 | |
| SCHEMBL2336147 | 0.84 | NR1H4 (0.42) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |