Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707635 | 0.93 | CTSA (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2P2RY12 | |
| SCHEMBL3704916 | 0.93 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2P2RY12 | |
| SCHEMBL1246290 | 0.87 | SCN9A (0.40) | ALDH1A1KDM4EHPGDP2RY12CTSA | |
| SCHEMBL3710286 | 0.86 | MAPT (0.40) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL2335317 | 0.85 | LPAR1 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2LPAR1 | |
| SCHEMBL3700514 | 0.85 | LPAR1 (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2CTSA | |
| SCHEMBL2336114 | 0.85 | LTB4R2 (0.37) | ALDH1A1KDM4EHPGDSMN1; SMN2ACR | |
| SCHEMBL3708659 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KDM4ESMN1; SMN2MAPTLPAR1 | |
| SCHEMBL3711161 | 0.83 | LDHA (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPT | |
| SCHEMBL2336147 | 0.83 | NR1H4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |