Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415949 | 0.79 | CHRM2 (0.67) | GAACHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL6566603 | 0.79 | GAA (0.56) | GAACHRM2SMN1; SMN2ALDH1A1DNM1 | |
| SCHEMBL3700676 | 0.79 | CHRM2 (0.52) | GAACHRM2SMN1; SMN2ALDH1A1DNM1 | |
| SCHEMBL3701547 | 0.78 | MEN1 (0.56) | GAACHRM2ALDH1A1DNM1MEN1 | |
| Hydrochloric Acid SCHEMBL7695180 | 0.77 | CHRM2 (0.64) | GAACHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL28471534 | 0.76 | IL6 (0.46) | GAAALDH1A1KCNH2 | |
| SCHEMBL11294244 | 0.76 | CYP1A2 (0.62) | GAACHRM2SMN1; SMN2ALDH1A1DNM1 | |
| SCHEMBL229169 | 0.76 | GAA (0.51) | GAASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL12652035 | 0.76 | CHRM2 (0.57) | GAACHRM2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11094422 | 0.75 | CHRM2 (0.75) | GAACHRM2SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638002-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2638002-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2638002-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | Bayer Intellectual Property GmbH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8450528-B2 | Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| US-8450528-B2 | Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| US-8450528-B2 | Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | HDHD5, CTRB2, H1-2 | GAA 2102/4885CHRM2 159/4885SMN1; SMN2 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.