Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | ADH1B | P00325 | 1/20 | 0.45 |
| ▸ | ADH1C | P00326 | 1/20 | 0.45 |
| ▸ | ADH1A | P07327 | 1/20 | 0.45 |
| ▸ | ADH7 | P40394 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793724 | 0.81 | MEN1 (0.50) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL13088683 | 0.81 | SIGMAR1 (0.50) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL25309628 | 0.79 | ANPEP (0.49) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL2224067 | 0.79 | ANPEP (0.49) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL3700676 | 0.78 | CHRM2 (0.52) | MEN1KMT2ACHRM2GAAMAPT | |
| SCHEMBL3700658 | 0.78 | GAA (0.61) | MEN1KMT2ATDP1CHRM2GAA | |
| SCHEMBL13088679 | 0.78 | ANPEP (0.60) | MEN1KMT2ATDP1ANPEPMAPT | |
| SCHEMBL8051013 | 0.77 | BCHE (0.60) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL7095555 | 0.77 | BCHE (0.60) | MEN1KMT2ATDP1ANPEPMAOA | |
| SCHEMBL2018449 | 0.77 | MEN1 (0.56) | MEN1KMT2ATDP1ANPEPMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638002-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | claimed |
| EP-2638002-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | Bayer Intellectual Property GmbH (DE) | 2013-09-18 | — | — | EP | claimed |
| US-8450528-B2 | Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | claimed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | claimed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | claimed |
| US-20240158335-A1 | A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS | University of Strasbourg (FR) | 2024-05-16 | — | — | US | disclosed |
| CN-116867765-A | Method for producing polyfluoroalkyl amines from polyfluoroalkyl alcohols | 拜耳公司 | 2023-10-10 | — | — | CN | disclosed |
| WO-2022175132-A1 | A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-08-25 | — | — | WO | disclosed |
| EP-2638002-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2638002-B1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER IP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| CN-103201251-B | By the method for benzylamine compound initial preparation 2,2-difluoroethylamine | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-02 | — | — | CN | disclosed |
| EP-2638002-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | Bayer Intellectual Property GmbH (DE) | 2013-09-18 | — | — | EP | disclosed |
| US-8450528-B2 | Process for the preparation of 2,2-difluoroethylamine starting from a benzylamine compound | BAYER CROPSCIENCE AG (DE) | 2013-05-28 | — | — | US | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062702-A1 | METHOD FOR PREPARING 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-18 | — | — | WO | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | BAYER CROPSCIENCE AG (DE) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123163-A1 | PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND | HDHD5, CTRB2, H1-2 | MEN1 1447/4885KMT2A 481/4885TDP1 3574/4885 |
| US-20240158335-A1 | A PROCESS FOR THE PREPARATION OF POLYFLUOROALKYLAMINES FROM POLYFLUOROALKYLALCOHOLS | PHF2, PFAS, PHF8 | MEN1 2703/4885KMT2A 363/4885TDP1 3629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.