SCHEMBL3701630

SCHEMBL3701630

COc1cc(C(C)(C)CCCC(C)C)cc(OC)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
CNR2 P34972 12/20 0.43
ALOX5 P09917 2/20 0.40
CNR1 P21554 9/20 0.39
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA3 P07451 1/20 0.36
CA4 P22748 1/20 0.36
CA6 P23280 1/20 0.36
CA5A P35218 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13819538 0.89 ALOX5 (0.41) PKMKDM4EALDH1A1GAAKMT2A
SCHEMBL6716285 0.87 CNR2 (0.43) KDM4EKMT2ACNR2CNR1CYP3A4
SCHEMBL27602008 0.83 CNR2 (0.48) KMT2ACNR2CNR1CYP1A2CYP3A4
SCHEMBL20929943 0.82 CNR2 (0.61) CNR2CNR1
SCHEMBL20930037 0.81 GAA (0.46) PKMKDM4EALDH1A1GAAKMT2A
SCHEMBL5430441 0.81 CNR2 (0.63) CNR2CNR1
SCHEMBL3705499 0.80 CNR2 (0.44) ALDH1A1KMT2ACNR2CNR1CA1
SCHEMBL13819539 0.80 CNR2 (0.40) PKMKDM4EALDH1A1GAAKMT2A
SCHEMBL3693693 0.79 CNR2 (0.45) CNR2CNR1
SCHEMBL3694612 0.78 CNR2 (0.42) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9173867-B2 Treatment of immune dysregulation using cannabinoid derivatives IMMUGEN PHARMACEUTICALS, INC. (US) 2015-11-03 US disclosed
US-9173867-B2 Treatment of immune dysregulation using cannabinoid derivatives IMMUGEN PHARMACEUTICALS, INC. (US) 2015-11-03 US disclosed
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES IMMUGEN PHARMACEUTICALS, INC. 2014-03-06 US disclosed
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES IMMUGEN PHARMACEUTICALS, INC. 2014-03-06 US disclosed
US-8586767-B2 Method for treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG RICK (US) 2013-11-19 US disclosed
US-8586767-B2 Method for treatment of HIV and diseases of immune dysregulation TRAVIS CRAIG RICK (US) 2013-11-19 US disclosed
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives TRAVIS CRAIG RICK (US) 2012-11-15 US disclosed
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives TRAVIS CRAIG RICK (US) 2012-11-15 US disclosed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 US disclosed
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation TRAVIS CRAIG RICK (US) 2012-05-17 US disclosed
US-6541510-B2 Cannabichromene derivative is exposed to the virus, a host cell, or an infected cell under conditions sufficient to inhibit the replication or proliferation of the virus, especially HIV. IMMUGEN PHARMACEUTICALS, INC. 2003-04-01 US disclosed
WO-2002026224-A9 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS INC (US) 2003-02-20 WO disclosed
US-20020137802-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation IMMUGEN PHARMACEUTICALS, INC. 2002-09-26 US disclosed
US-20020068738-A1 Antiviral methods and compounds IMMUGEN PHARMACEUTICALS, INC. 2002-06-06 US disclosed
WO-2002026728-A2 ANTIVIRAL METHODS AND COMPOUNDS IMMUGEN PHARMACEUTICALS, INC. (US) 2002-04-04 WO disclosed
WO-2002026224-A2 METHODS AND COMPOUNDS FOR INHIBITING EICOSANOID METABOLISM AND PLATELET AGGREGATION IMMUGEN PHARMACEUTICALS, INC. (US) 2002-04-04 WO disclosed
US-20020037923-A1 Resorcinolic compounds IMMUGEN PHARMACEUTICALS, INC. 2002-03-28 US disclosed
EP-1189603-A2 TREATMENT OF IMMUNE DISEASES LIKE HIV DISEASE AND NEOPLASTIC DISORDERS Immugen Pharmaceuticals, Inc. (US) 2002-03-27 EP disclosed
US-6274635-B1 ANTITUMOR AGENTS IMMUGEN PHARMACEUTICALS INC. 2001-08-14 US disclosed
WO-2000056303-A2 TREATMENT OF IMMUNE DISEASES IMMUGEN PHARMACEUTICALS, INC. (US) 2000-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140066497-A1 TREATMENT OF IMMUNE DYSREGULATION USING CANNABINOID DERIVATIVES CNR2, CNR1, GPR18 PKM 4037/4885KDM4E 789/4885ALDH1A1 3563/4885
US-20020037923-A1 Resorcinolic compounds VHL, HRAS, CYP46A1 PKM 3878/4885KDM4E 4081/4885ALDH1A1 1839/4885
US-20020068738-A1 Antiviral methods and compounds MAVS, CNR1, ZC3HAV1 PKM 4251/4885KDM4E 1875/4885ALDH1A1 3995/4885
US-20120289589-A1 Treatment Of Immune Dysregulation Using Cannabinoid Derivatives CNR2, CNR1, GPR18 PKM 4037/4885KDM4E 789/4885ALDH1A1 3563/4885
US-20120122917-A1 Method For Treatment Of HIV And Diseases Of Immune Dysregulation CNR2, CNR1, ICOS PKM 3249/4885KDM4E 479/4885ALDH1A1 3303/4885
US-20020137802-A1 Methods and compounds for inhibiting eicosanoid metabolism and platelet aggregation PTGS1, PTGIS, PTGES PKM 3223/4885KDM4E 4027/4885ALDH1A1 678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.