Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 5/20 | 0.46 |
| ▸ | CA9 | Q16790 | 5/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.46 |
| ▸ | CA3 | P07451 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA6 | P23280 | 3/20 | 0.46 |
| ▸ | CA5A | P35218 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370180 | 1.00 | POLB (0.49) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL4371962 | 0.86 | MMP9 (0.50) | POLBCA1CA2CA12CA9 | |
| SCHEMBL10867412 | 0.86 | MMP9 (0.50) | POLBCA1CA2CA12CA9 | |
| SCHEMBL15630892 | 0.84 | POLB (0.51) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL10615659 | 0.84 | POLB (0.51) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL15631944 | 0.84 | POLB (0.51) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL10012970 | 0.82 | ALDH1A1 (0.46) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL19469361 | 0.82 | CA2 (0.52) | POLBF2PRSS1PRSS2PRSS3 | |
| SCHEMBL8874363 | 0.81 | RAB9A (0.49) | POLBALDH1A1HSP90AA1KMT2AMAPT | |
| SCHEMBL8874371 | 0.81 | RAB9A (0.49) | POLBALDH1A1HSP90AA1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835685-B2 | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2014-09-16 | — | — | US | claimed |
| EP-2593423-B1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2014-09-03 | — | — | EP | claimed |
| US-20130131382-A1 | Process For The Preparation Of Contrast Agents | BRACCO IMAGING S.P.A. (IT) | 2013-05-23 | — | — | US | claimed |
| EP-2593423-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | Bracco Imaging S.p.A (IT) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007547-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2012-01-19 | — | — | WO | claimed |
| US-8835685-B2 | Process for the preparation of contrast agents | BRACCO IMAGING S.P.A. (IT) | 2014-09-16 | — | — | US | disclosed |
| EP-2593423-B1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING SPA (IT) | 2014-09-03 | — | — | EP | disclosed |
| US-20130131382-A1 | Process For The Preparation Of Contrast Agents | BRACCO IMAGING S.P.A. (IT) | 2013-05-23 | — | — | US | disclosed |
| EP-2593423-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | Bracco Imaging S.p.A (IT) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007547-A1 | PROCESS FOR THE PREPARATION OF CONTRAST AGENTS | BRACCO IMAGING S.P.A. (IT) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131382-A1 | Process For The Preparation Of Contrast Agents | SLC1A5, SLC30A5, SLC9B2 | POLB 1367/4885F2 2719/4885PRSS1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.