Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 4/20 | 0.53 |
| ▸ | DGKA | P23743 | 1/20 | 0.49 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11148184 | 0.96 | TLR4 (0.56) | TLR4HSD17B10FABP4PPARGPPARD | |
| SCHEMBL20873457 | 0.92 | TLR4 (0.49) | TLR4DGKATERTPTPN1CYP1A2 | |
| SCHEMBL1961137 | 0.90 | TLR4 (0.54) | TLR4DGKATERTPTPN1CYP1A2 | |
| SCHEMBL30980017 | 0.90 | DGKA (0.49) | TLR4DGKAMAPTFAAH | |
| SCHEMBL25366931 | 0.89 | TLR4 (0.62) | TLR4DGKACYP1A2MAPTCYP2C19 | |
| SCHEMBL4597674 | 0.88 | NAAA (0.50) | TLR4DGKA | |
| SCHEMBL467559 | 0.88 | NAAA (0.50) | TLR4DGKA | |
| SCHEMBL29694364 | 0.87 | TERT (0.54) | TLR4TERTPTPN1CYP1A2MAPT | |
| SCHEMBL1934663 | 0.85 | TLR4 (0.64) | TLR4HSD17B10FABP4PPARGPPARD | |
| SCHEMBL11436002 | 0.84 | TERT (0.51) | TLR4TERTPTPN1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8795547-B2 | Refrigeration oil from gas-to-liquid-derived and bio-derived triesters | CHEVRON U.S.A. INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130256586-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED TRIESTERS | CHEVRON U.S.A., INC. | 2013-10-03 | — | — | US | disclosed |
| EP-2227529-A2 | REFRIGERATION OIL FROM GAS-TO-LIQUID DERIVED AND BIO-DERIVED TRIESTERS | Chevron U.S.A. Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| EP-2132283-A1 | TRIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | Chevron U.S.A., Inc. (US) | 2009-12-16 | — | — | EP | disclosed |
| WO-2009085855-A2 | REFRIGERATION OIL FROM GAS-TO-LIQUID DERIVED AND BIO-DERIVED TRIESTERS | CHEVRON U.S.A. INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| US-20090159835-A1 | REFRIGERATION OIL FROM GAS-TO-LIQUID-DERIVED AND BIO-DERIVED TRIESTERS | CHEVRON U.S.A., INC. | 2009-06-25 | — | — | US | disclosed |
| US-7544645-B2 | Triester-based lubricants and methods of making same | CHEVRON U.S.A. INC. (US) | 2009-06-09 | — | — | US | disclosed |
| WO-2008124294-A1 | TRIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON U.S.A. INC. (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20080248982-A1 | TRIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | CHEVRON U.S.A. INC. (US) | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080248982-A1 | TRIESTER-BASED LUBRICANTS AND METHODS OF MAKING SAME | ADH5, ADH1A, ELOVL5 | TLR4 1502/4885DGKA 165/4885TERT 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.