SCHEMBL3702855

SCHEMBL3702855

C=C(F)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 12/20 0.50
NR1H2 P55055 11/20 0.50
MLYCD O95822 6/20 0.47
RORC P51449 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL86047 0.81 NR1H3 (0.53) NR1H3NR1H2MLYCD
SCHEMBL131990 0.81 NR1H2 (0.68) NR1H3NR1H2MLYCD
Water SCHEMBL1684070 0.78 NR1H2 (0.65) NR1H3NR1H2MLYCD
SCHEMBL128398 0.75 NR1H2 (0.56) NR1H3NR1H2MLYCD
SCHEMBL1512711 0.74 SRD5A2 (0.59) NR1H3NR1H2MLYCDRORC
SCHEMBL24901413 0.74 NR1H2 (0.61) NR1H3NR1H2MLYCDRORC
SCHEMBL9621271 0.74 NR1H2 (0.60) NR1H3NR1H2MLYCDRORC
SCHEMBL13100303 0.72 SMN1; SMN2 (0.59) NR1H3NR1H2MLYCDRORC
SCHEMBL31078115 0.72 MLYCD (0.54) NR1H3NR1H2MLYCDRORC
SCHEMBL4867933 0.72 MLYCD (0.54) NR1H3NR1H2MLYCDRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1720063-B1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO (JP) 2010-04-07 EP disclosed
EP-1482361-B1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO (JP) 2007-10-03 EP disclosed
EP-1720063-A1 Resin containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-11-08 EP disclosed
US-7105272-B2 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2006-09-12 US disclosed
US-20050130057-A1 Acid-degradable resin compositions containing ketene-aldehyde copolymer NIPPON SODA CO., LTD. (JP) 2005-06-16 US disclosed
EP-1482361-A1 ACID-DEGRADABLE RESIN COMPOSITIONS CONTAINING KETENE-ALDEHYDE COPOLYMER NIPPON SODA CO., LTD. (JP) 2004-12-01 EP disclosed