Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RGS12 | O14924 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443870 | 0.91 | TRPA1 (0.62) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL727024 | 0.91 | TRPA1 (0.62) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL18116476 | 0.84 | EGFR (0.58) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL12203362 | 0.84 | ESR1 (0.60) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL24110743 | 0.82 | TRPA1 (0.58) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL29696089 | 0.82 | APP (0.59) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL22991659 | 0.82 | APP (0.59) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL151119 | 0.80 | TUBB1 (0.59) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL3847926 | 0.80 | TUBB1 (0.59) | TRPA1EGFRMAPTKMT2ACYP3A4 | |
| SCHEMBL22917545 | 0.80 | ERN1 (0.62) | TRPA1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645492-B1 | PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS | UNIV LEUVEN KATH (BE) | 2024-08-21 | — | — | EP | claimed |
| CN-110809570-B | Preparation method of ortho-alkoxy bisphenol monomer | 鲁汶天主教大学 | 2023-06-23 | — | — | CN | claimed |
| US-11414519-B2 | Ortho alkoxy bisphenol monomers | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-08-16 | — | — | US | claimed |
| EP-3645492-A1 | PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS | Katholieke Universiteit Leuven (BE) | 2020-05-06 | — | — | EP | claimed |
| US-20200123315-A1 | ORTHO ALKOXY BISPHENOL MONOMERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2020-04-23 | — | — | US | claimed |
| CN-110809570-A | Preparation method of ortho-alkoxy bisphenol monomer | 鲁汶天主教大学 | 2020-02-18 | — | — | CN | claimed |
| WO-2019002503-A1 | PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2019-01-03 | — | — | WO | claimed |
| EP-4455188-A2 | PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS | Katholieke Universiteit Leuven KU Leuven Research & Development (BE) | 2024-10-30 | — | — | EP | disclosed |
| EP-3645492-B1 | PREPARATION PROCESS OF ORTHO ALKOXY BISPHENOL MONOMERS | UNIV LEUVEN KATH (BE) | 2024-08-21 | — | — | EP | disclosed |
| CN-110809570-B | Preparation method of ortho-alkoxy bisphenol monomer | 鲁汶天主教大学 | 2023-06-23 | — | — | CN | disclosed |
| US-11414519-B2 | Ortho alkoxy bisphenol monomers | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-08-16 | — | — | US | disclosed |
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | KEMPHARM, INC. (US) | 2022-02-01 | — | — | US | disclosed |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | ALTER DOMUS (US) LLC | 2021-01-07 | — | — | US | disclosed |
| US-9850252-B2 | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone, prodrugs, methods of making and use thereof | KEMPHARM, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | ALTER DOMUS (US) LLC | 2017-11-02 | — | — | US | disclosed |
| US-20170049765-A1 | Methylphenidate-Prodrugs, Processes of Making and Using the Same | COMMAVE THERAPEUTICS SA (CH) | 2017-02-23 | — | — | US | disclosed |
| EP-2453311-B1 | Toner for developing electrostatic image and manufacturing method of toner for developing electrostatic image | KONICA MINOLTA BUSINESS TECH (JP) | 2013-12-25 | — | — | EP | disclosed |
| CN-102540791-B | Toner for developing electrostatic image and manufacturing method of toner for developing electrostatic image | KONICA MINOLTA BUSINESS TECH | 2013-10-16 | — | — | CN | disclosed |
| CN-102540791-A | Toner for developing electrostatic image and manufacturing method of toner for developing electrostatic image | KONICA MINOLTA BUSINESS TECH | 2012-07-04 | — | — | CN | disclosed |
| EP-2453311-A1 | Toner for developing electrostatic image and manufacturing method of toner for developing electrostatic image | Konica Minolta Business Technologies, Inc. (JP) | 2012-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170312270-A1 | BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF OXYMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF | OPRM1, OPRK1, OPRD1 | TRPA1 2443/4885EGFR 2553/4885MAPT 2959/4885 |
| US-20170049765-A1 | Methylphenidate-Prodrugs, Processes of Making and Using the Same | COMT, TPMT, PNMT | TRPA1 4133/4885EGFR 2414/4885MAPT 406/4885 |
| US-11234975-B2 | Levorphanol prodrugs and processes for making and using them | OPRM1, OPRL1, OPRK1 | TRPA1 3428/4885EGFR 4271/4885MAPT 2539/4885 |
| US-11414519-B2 | Ortho alkoxy bisphenol monomers | ALK, ESR1, ADIPOR1 | TRPA1 234/4885EGFR 3523/4885MAPT 180/4885 |
| US-20210002226-A1 | LEVORPHANOL PRODRUGS AND PROCESSES FOR MAKING AND USING THEM | OPRM1, OPRK1, OPRD1 | TRPA1 3204/4885EGFR 4498/4885MAPT 2545/4885 |
| US-20200123315-A1 | ORTHO ALKOXY BISPHENOL MONOMERS | ALK, ESR1, ADIPOR1 | TRPA1 234/4885EGFR 3523/4885MAPT 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.