Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389959 | 0.82 | FFAR1 (0.35) | FFAR1HIF1APTGER4PTGER2 | |
| SCHEMBL1389962 | 0.82 | FFAR1 (0.35) | FFAR1HIF1APTGER4PTGER2 | |
| SCHEMBL363129 | 0.80 | FFAR1 (0.34) | FFAR1HIF1APTGER4PTGER2 | |
| SCHEMBL370503 | 0.78 | GPBAR1 (0.46) | PTGER4PTGER2 | |
| SCHEMBL371041 | 0.76 | FFAR1 (0.37) | FFAR1HIF1APTGER4PTGER2 | |
| SCHEMBL10291213 | 0.75 | FFAR1 (0.36) | FFAR1HIF1APTGER4PTGER2 | |
| SCHEMBL369177 | 0.75 | GPBAR1 (0.33) | — | |
| SCHEMBL362921 | 0.73 | MRGPRX4 (0.40) | PTGER4PTGER2 | |
| SCHEMBL362920 | 0.73 | MRGPRX4 (0.40) | PTGER4PTGER2 | |
| SCHEMBL370096 | 0.72 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |