Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370059 | 0.90 | GPBAR1 (0.35) | FFAR1CHEK2GPBAR1ADRB1ADRB3 | |
| SCHEMBL363394 | 0.89 | MRGPRX4 (0.40) | PTGER4PTGER2KDRGPBAR1ADRB1 | |
| SCHEMBL363628 | 0.88 | ADRB1 (0.35) | FFAR1PTGER4PTGER2KDRGPBAR1 | |
| SCHEMBL1389959 | 0.85 | FFAR1 (0.35) | FFAR1PTGER4PTGER2CHEK2GPBAR1 | |
| SCHEMBL1389962 | 0.85 | FFAR1 (0.35) | FFAR1PTGER4PTGER2CHEK2GPBAR1 | |
| SCHEMBL362499 | 0.83 | PPARG (0.32) | GPBAR1 | |
| SCHEMBL364251 | 0.82 | MEN1 (0.35) | FFAR1GPBAR1 | |
| SCHEMBL370370 | 0.80 | FFAR1 (0.33) | FFAR1PTGER4PTGER2HIF1A | |
| SCHEMBL365756 | 0.80 | ADRB3 (0.38) | GPBAR1ADRB1ADRB3MRGPRX4 | |
| SCHEMBL365274 | 0.79 | GPBAR1 (0.46) | GPBAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | claimed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | claimed |
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |