Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704670 | 0.93 | TSHR (0.40) | POLBTSHRPRSS12MAPTHTT | |
| SCHEMBL3704908 | 0.92 | MAPT (0.39) | POLBMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL3705791 | 0.90 | STAT3 (0.44) | PRSS12HPGDSTAT3F2F10 | |
| SCHEMBL3223086 | 0.90 | POLB (0.50) | POLBTSHRMAPTHTTNPSR1 | |
| SCHEMBL3704933 | 0.88 | NR3C1 (0.38) | POLBTSHRMAPTHTTNPSR1 | |
| SCHEMBL3223460 | 0.87 | POLB (0.49) | POLBMAPTHTTNPSR1ALDH1A1 | |
| SCHEMBL3715784 | 0.87 | TSHR (0.39) | TSHRMAPTLPAR1LPAR2HPGD | |
| SCHEMBL3705439 | 0.85 | TSPO (0.38) | TSHRMAPTHTTALDH1A1HPGD | |
| SCHEMBL3714771 | 0.83 | ESR1 (0.38) | TSHRMAPTHTTALDH1A1LPAR1 | |
| SCHEMBL3703153 | 0.82 | THRB (0.45) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |