Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.38 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3705581 | 0.90 | KDM4E (0.40) | KDM4EALDH1A1GLAMAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL3656579 | 0.87 | BCL9 (0.37) | AVPR2 | |
| SCHEMBL3657515 | 0.85 | RAB9A (0.41) | KDM4EALDH1A1GLAMAPTKMT2A | |
| Trifluoroacetic Acid SCHEMBL3657521 | 0.84 | MEN1 (0.42) | KDM4EALDH1A1MAPTKMT2AMCL1 | |
| Trifluoroacetic Acid SCHEMBL3654963 | 0.84 | — | — | |
| Trifluoroacetic Acid SCHEMBL3659571 | 0.83 | RAB9A (0.45) | ALDH1A1MAPTKMT2AMCL1RAB9A | |
| Trifluoroacetic Acid SCHEMBL3653624 | 0.83 | KDM4E (0.40) | KDM4EALDH1A1MAPTMCL1 | |
| Trifluoroacetic Acid SCHEMBL3654346 | 0.82 | JAK3 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL3654252 | 0.82 | FLT3 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL3653109 | 0.80 | RAB9A (0.45) | ALDH1A1MAPTKMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212282-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009052065-A1 | SUBSTITUTED N-PHENYL-BIPYRROLIDINE CARBOXAMIDES AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-04-23 | — | — | WO | disclosed |