Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3703610 | 0.90 | ALDH1A1 (0.44) | HPGDALDH1A1GAANPC1NPSR1 | |
| SCHEMBL3705716 | 0.89 | THRB (0.46) | HPGD | |
| SCHEMBL3713137 | 0.83 | MAPT (0.46) | ALDH1A1GAANPC1KDM4EMAPT | |
| SCHEMBL3807594 | 0.80 | SLC6A9 (0.42) | HPGDNPC1HTTKDM4EMEN1 | |
| SCHEMBL3800984 | 0.80 | GYS1 (0.41) | HPGDHTT | |
| SCHEMBL3713941 | 0.78 | THRB (0.50) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL3804919 | 0.78 | SLC6A9 (0.39) | HPGDNPC1HTTMEN1KMT2A | |
| SCHEMBL3803403 | 0.77 | SLC6A9 (0.39) | HPGDALDH1A1HTT | |
| SCHEMBL3806836 | 0.77 | KDM4E (0.41) | HPGDNPC1HTTKDM4EPOLB | |
| SCHEMBL3705084 | 0.75 | TSHR (0.44) | ALDH1A1GAANPC1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | disclosed |