Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713137 | 0.91 | MAPT (0.46) | TSHRALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3711114 | 0.85 | TSHR (0.44) | TSHRALDH1A1KMT2ASMN1; SMN2GAA | |
| SCHEMBL3711487 | 0.84 | POLB (0.44) | TSHRALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3705439 | 0.82 | TSPO (0.38) | TSHRALDH1A1MAPTKMT2AGAA | |
| SCHEMBL3707230 | 0.81 | LMNA (0.36) | TSHRALDH1A1MAPTKMT2AGAA | |
| SCHEMBL3707649 | 0.81 | THRB (0.42) | TSHRMAPTSMN1; SMN2GAATHRB | |
| SCHEMBL3703153 | 0.80 | THRB (0.45) | THRB | |
| SCHEMBL3715784 | 0.79 | TSHR (0.39) | TSHRMAPTKMT2AMEN1LMNA | |
| SCHEMBL3714771 | 0.79 | ESR1 (0.38) | TSHRALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3706682 | 0.79 | THRB (0.39) | MAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086878-A2 | THYROID RECEPTOR MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2010-08-05 | — | — | WO | claimed |