Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709238 | 0.93 | LPAR1 (0.41) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL3707582 | 0.92 | LPAR1 (0.39) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL2339543 | 0.90 | LPAR1 (0.42) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL3704465 | 0.88 | TBXAS1 (0.36) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL3702066 | 0.88 | POLB (0.37) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL3714445 | 0.87 | LPAR1 (0.38) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL3704161 | 0.87 | LPAR1 (0.47) | LPAR1LPAR2LPAR3HTTALDH1A1 | |
| SCHEMBL2334024 | 0.86 | L3MBTL1 (0.38) | LPAR1LPAR2LPAR3HTTL3MBTL1 | |
| SCHEMBL2341943 | 0.85 | CYP4F2 (0.39) | LPAR1LPAR2LPAR3ALDH1A1ALOX5 | |
| SCHEMBL2336634 | 0.85 | LPAR1 (0.43) | LPAR1LPAR2LPAR3HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |