Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707308 | 0.94 | CFD (0.40) | HPGDALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3706733 | 0.88 | LPAR1 (0.36) | HPGDALDH1A1NPSR1LPAR1LPAR2 | |
| SCHEMBL2339543 | 0.87 | LPAR1 (0.42) | HPGDALDH1A1LPAR1LPAR2LPAR3 | |
| SCHEMBL3707582 | 0.86 | LPAR1 (0.39) | HPGDALDH1A1LPAR1LPAR2LPAR3 | |
| SCHEMBL3714445 | 0.84 | LPAR1 (0.38) | TBXAS1HPGDALDH1A1LPAR1LPAR2 | |
| SCHEMBL3708634 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LPAR1LPAR2LPAR3L3MBTL1 | |
| SCHEMBL3702563 | 0.84 | NR1H4 (0.46) | LPAR1LPAR2LPAR3ALOX5ALOX5AP | |
| SCHEMBL2342065 | 0.82 | PPARD (0.40) | LPAR1LPAR2LPAR3ALOX15CRHBP | |
| SCHEMBL2336634 | 0.82 | LPAR1 (0.43) | HPGDALDH1A1LPAR1LPAR2LPAR3 | |
| SCHEMBL2341943 | 0.82 | CYP4F2 (0.39) | HPGDALDH1A1MEN1KMT2ALPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |