Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL28409875 | 0.98 | TP53 (0.52) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| Lactic Acid SCHEMBL28582874 | 0.95 | TP53 (0.50) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| Lactic Acid SCHEMBL4061613 | 0.95 | TP53 (0.50) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| Hydrogen Peroxide SCHEMBL5367632 | 0.95 | ALDH1A1 (0.48) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| Lactic Acid SCHEMBL5697793 | 0.93 | TP53 (0.48) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| Bicarbonate SCHEMBL28391088 | 0.92 | ALDH1A1 (0.46) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL22598 | 0.92 | — | — | |
| SCHEMBL29615225 | 0.92 | — | — | |
| SCHEMBL471892 | 0.92 | ALDH1A1 (0.50) | TP53ALDH1A1LMNAHSD17B10ALOX15 | |
| SCHEMBL344175 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240141502-A1 | METAL SURFACE TREATMENT AGENT | HITACHI, LTD. (JP) | 2024-05-02 | — | — | US | disclosed |
| CN-219804615-U | Catalytic reactor for preparing ethyl lactate from lactic acid | 天津中福环保科技股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-219804615-U | Catalytic reactor for preparing ethyl lactate from lactic acid | 天津中福环保科技股份有限公司 | 2023-10-10 | — | — | CN | disclosed |
| US-20210253814-A1 | ORGANOSILANE COATING COMPOSITIONS | HENKEL AG & CO. KGAA (DE) | 2021-08-19 | — | — | US | disclosed |
| EP-3793750-A1 | ORGANOSILANE COATING COMPOSITIONS | NBD Nanotechnologies, Inc. (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20200208012-A1 | ADHESION PROMOTERS AND THEIR USE | HENKEL AG & CO. KGAA (DE) | 2020-07-02 | — | — | US | disclosed |
| EP-3672798-A1 | ADHESION PROMOTERS AND THEIR USE | NBD Nanotechnologies, Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2019040922-A1 | ADHESION PROMOTERS AND THEIR USE | NBD NANOTECHNOLOGIES, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | NITRO-CHEME ASCHAU GmbH (DE) | 2012-01-19 | — | — | US | disclosed |
| US-7968276-B2 | Positive resist composition and method of forming resist pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2011-06-28 | — | — | US | disclosed |
| US-20090181325-A1 | POSITIVE RESIST COMPOSITION AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-0722469-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF LACTIDE AND LACTIDE POLYMERS | CARGILL, INCORPORATED (US) | 1996-07-24 | — | — | EP | disclosed |
| WO-1995009879-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF LACTIDE AND LACTIDE POLYMERS | CARGILL, INCORPORATED (US) | 1995-04-13 | — | — | WO | disclosed |
| EP-0623153-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF LACTIDE AND LACTIDE POLYMERS | CARGILL, INCORPORATED (US) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993015127-A1 | CONTINUOUS PROCESS FOR THE MANUFACTURE OF LACTIDE AND LACTIDE POLYMERS | CARGILL, INCORPORATED (US) | 1993-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | HACD2, HACD3, ITGA2 | TP53 3523/4885ALDH1A1 559/4885LMNA 2007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.