Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | TAF1 | P21675 | 1/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.37 |
| ▸ | CFB | P00751 | 8/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893431 | 0.80 | BRD4 (0.36) | IMPDH2IMPDH1XDHSLC22A12PRKCQ | |
| SCHEMBL8530077 | 0.78 | IMPDH2 (0.50) | IMPDH2IMPDH1XDHSLC22A12RIPK1 | |
| SCHEMBL16636645 | 0.78 | IMPDH2 (0.50) | IMPDH2IMPDH1XDHSLC22A12RIPK1 | |
| SCHEMBL988243 | 0.78 | IMPDH2 (0.50) | IMPDH2IMPDH1XDHSLC22A12RIPK1 | |
| SCHEMBL28597933 | 0.76 | XDH (0.50) | IMPDH2IMPDH1XDHSLC22A12RIPK1 | |
| SCHEMBL21920740 | 0.75 | IMPDH2 (0.44) | IMPDH2IMPDH1XDHSLC22A12RIPK1 | |
| SCHEMBL18876107 | 0.74 | L3MBTL1 (0.38) | IMPDH2IMPDH1IKBKBCHUKBRD4 | |
| SCHEMBL4798726 | 0.74 | CYP1A2 (0.40) | IKBKBCHUKBRD4TAF1BRPF1 | |
| SCHEMBL18876117 | 0.73 | KDM4E (0.37) | IMPDH2IMPDH1XDHSLC22A12IKBKB | |
| SCHEMBL12585067 | 0.73 | XDH (0.64) | IMPDH2IMPDH1XDHSLC22A12IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |
| US-5523312-A | ADMINISTERING TO MAMMALS | STERLING WINTHROP INC. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5514692-A | VIRICIDES | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996009822-A1 | ANTIPICORNAVIRAL AGENTS | SANOFI WINTHROP, INC. (US) | 1996-04-04 | — | — | WO | disclosed |