Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 7/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.36 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704465 | 0.94 | TBXAS1 (0.36) | CFDLPAR1LPAR2LPAR3FFAR4 | |
| SCHEMBL3702563 | 0.89 | NR1H4 (0.46) | LPAR1LPAR2LPAR3PPARDFABP4 | |
| SCHEMBL3709238 | 0.88 | LPAR1 (0.41) | LPAR1LPAR2LPAR3PPARDFFAR4 | |
| SCHEMBL2338262 | 0.87 | LPAR1 (0.50) | LPAR1LPAR2LPAR3PPARDFABP4 | |
| SCHEMBL1246460 | 0.87 | PPARD (0.39) | CFDPPARDFFAR4FABP4FABP5 | |
| SCHEMBL2342592 | 0.87 | LPAR1 (0.39) | LPAR1LPAR2LPAR3PPARDHPGD | |
| SCHEMBL3704161 | 0.86 | LPAR1 (0.47) | LPAR1LPAR2LPAR3PPARDFABP4 | |
| SCHEMBL3703134 | 0.85 | LPAR1 (0.39) | LPAR1LPAR2LPAR3PPARDFFAR4 | |
| SCHEMBL3707791 | 0.84 | LPAR1 (0.38) | LPAR1LPAR2LPAR3HPGDNPSR1 | |
| SCHEMBL3700609 | 0.84 | LPAR1 (0.46) | LPAR1LPAR2LPAR3PPARDFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| WO-2010077882-A2 | ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |