Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3706388 | 0.84 | HTR4 (0.34) | HTR4GLACA12CA1CA2 | |
| SCHEMBL3703407 | 0.81 | TSHR (0.34) | HTR4SMN1; SMN2LIPEALDH1A1 | |
| SCHEMBL3707781 | 0.78 | GNAI3 (0.41) | — | |
| SCHEMBL3699860 | 0.78 | KDM1A (0.33) | HTR4GLAKDM1A | |
| SCHEMBL935658 | 0.73 | TSHR (0.34) | HTR4SMN1; SMN2LIPEALDH1A1 | |
| SCHEMBL3712866 | 0.71 | HTR4 (0.34) | HTR4GLAKDM1AALDH1A1 | |
| SCHEMBL1861629 | 0.70 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL13451264 | 0.69 | TDP1 (0.47) | HTR4SMN1; SMN2LIPEKDM1AALDH1A1 | |
| SCHEMBL658288 | 0.69 | — | — | |
| SCHEMBL936005 | 0.68 | HTR4 (0.34) | HTR4GLACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357755-B2 | Cross-linkable organosilicon-based compositions | WACKER CHEMIE AG (DE) | 2013-01-22 | — | — | US | disclosed |
| US-20120123048-A1 | CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS | WACKER CHEMIE AG (DE) | 2012-05-17 | — | — | US | disclosed |