Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 11/20 | 0.46 |
| ▸ | SLC16A1 | P53985 | 10/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3698799 | 0.83 | SLC16A3 (0.40) | SLC16A3SLC16A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3709000 | 0.81 | SLC16A3 (0.37) | SLC16A3SLC16A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3701193 | 0.80 | RIPK1 (0.44) | SLC16A3SLC16A1MEN1KMT2ARIPK1 | |
| SCHEMBL4130908 | 0.78 | SLC16A3 (0.46) | SLC16A3SLC16A1MEN1KMT2ARIPK1 | |
| SCHEMBL4130915 | 0.78 | SLC16A3 (0.41) | SLC16A3SLC16A1MEN1KMT2ARIPK1 | |
| SCHEMBL3696581 | 0.78 | SLC16A3 (0.38) | SLC16A3SLC16A1MEN1KMT2ARIPK1 | |
| SCHEMBL3696583 | 0.76 | HTR2C (0.51) | SLC16A3SLC16A1 | |
| SCHEMBL3707175 | 0.73 | SLC6A9 (0.33) | MAPTLMNA | |
| SCHEMBL2839606 | 0.69 | SLC6A4 (0.38) | SLC16A3SLC16A1KMT2ARIPK1MAPT | |
| SCHEMBL4125828 | 0.69 | P2RX7 (0.39) | SLC16A3SLC16A1KMT2ARIPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190822-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009041705-A2 | 5-MEMBERED HETEROCYCLIC COMPOUNDS AS PROTON PUMP INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-04-02 | — | — | WO | disclosed |