SCHEMBL3708779

SCHEMBL3708779

CCO[Si](C)(CNN1CCNCC1)OCC

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 2/20 0.42
GNAO1 P09471 2/20 0.42
GNAI1 P63096 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL936231 0.84 GNAI3 (0.43) GNAI3GNAO1GNAI1
SCHEMBL3707781 0.81 GNAI3 (0.41) GNAI3GNAO1GNAI1
SCHEMBL3702867 0.80 GNAI3 (0.53) GNAI3GNAO1GNAI1
SCHEMBL3703407 0.80 TSHR (0.34)
SCHEMBL27873396 0.75 GNAI3 (0.46) GNAI3GNAO1GNAI1
SCHEMBL538138 0.72 SIGMAR1 (0.36)
SCHEMBL935505 0.72 GNAI3 (0.42) GNAI3GNAO1GNAI1
SCHEMBL934568 0.71 GNAI3 (0.54) GNAI3GNAO1GNAI1
SCHEMBL4005712 0.70 SIGMAR1 (0.35)
SCHEMBL1537342 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357755-B2 Cross-linkable organosilicon-based compositions WACKER CHEMIE AG (DE) 2013-01-22 US disclosed
US-20120123048-A1 CROSS-LINKABLE ORGANOSILICON-BASED COMPOSITIONS WACKER CHEMIE AG (DE) 2012-05-17 US disclosed