SCHEMBL538138

SCHEMBL538138

CCO[Si](C)(CN1CCNCC1)OCC

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.32
POLB P06746 1/20 0.31
CXCR4 P61073 1/20 0.31
CHRM5 P08912 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4005712 0.98 SIGMAR1 (0.35) SIGMAR1SMN1; SMN2POLB
SCHEMBL4002631 0.84 SIGMAR1 (0.33) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL557566 0.82 SIGMAR1 (0.33) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL2502894 0.81
SCHEMBL4063799 0.81 SIGMAR1 (0.37) SIGMAR1SMN1; SMN2POLBCXCR4
SCHEMBL1519033 0.80 CYP1A2 (0.33) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5
SCHEMBL776777 0.79 TSHR (0.38) SIGMAR1SMN1; SMN2POLBCXCR4
SCHEMBL1992740 0.79 HRH3 (0.31)
SCHEMBL2501931 0.79 HRH3 (0.31)
SCHEMBL538013 0.79 CYP1A2 (0.34) SIGMAR1SMN1; SMN2POLBCXCR4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9758689-B2 Silver nanoparticle inks comprising aminomethylsilanes XEROX CORPORATION (US) 2017-09-12 US claimed
US-20150056383-A1 High Resolution Printing INTRINSIQ MATERIALS LTD. (GB) 2015-02-26 US claimed
EP-2742783-A1 HIGH RESOLUTION PRINTING Intrinsiq Materials Limited UK (GB) 2014-06-18 EP claimed
WO-2013024280-A1 HIGH RESOLUTION PRINTING INTRINSIQ MATERIALS LTD (GB) 2013-02-21 WO claimed
US-7569691-B2 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. (JP) 2009-08-04 US claimed
US-12545809-B2 Moisture-curing conformal coating compositions WACKER CHEMIE AG (DE) 2026-02-10 US disclosed
EP-4172246-B1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2024-08-07 EP disclosed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US disclosed
US-12018122-B2 Method for producing silane-modified polymers MERZ+BENTELI AG (CH) 2024-06-25 US disclosed
US-20230279263-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS WACKER CHEMIE AG (DE) 2023-09-07 US disclosed
EP-3877438-B1 METHOD FOR THE PREPARATION OF SILANE-MODIFIED POLYMERS MERZ BENTELI AG (CH) 2023-06-14 EP disclosed
EP-4172246-A1 MOISTURE-CURING CONFORMAL COATING COMPOSITIONS Wacker Chemie AG (DE) 2023-05-03 EP disclosed
EP-1824904-A1 ALKOXYSILANE-TERMINATED PREPOLYMERS Wacker Chemie AG (DE) 2007-08-29 EP disclosed
WO-2007048691-A2 PARTICLES COMPRISING ZWITTERIONIC STRUCTURAL ELEMENTS WACKER CHEMIE AG (DE) 2007-05-03 WO disclosed
US-20070042917-A1 Amine Tungstates and Lubricant Compositions KING INDUSTRIES, INC. 2007-02-22 US disclosed
WO-2007009022-A2 AMINE TUNGSTATES AND LUBRICANT COMPOSITIONS KING INDUSTRIES, INC. (US) 2007-01-18 WO disclosed
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method SHIN-ETSU CHEMICAL CO., LTD. 2006-10-26 US disclosed
EP-1714968-A1 Protected piperazino group-bearing organoxysilane compound and making method Shin-Etsu Chemical Co., Ltd. (JP) 2006-10-25 EP disclosed
WO-2006061091-A2 HIGHLY REACTIVE $G(A)-AMINOMETHYL-ALKOXYSILANES HAVING IMPROVED STABILITY WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed
WO-2006061090-A1 ALKOXYSILANE-TERMINATED PREPOLYMERS WACKER CHEMIE AG (DE) 2006-06-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241294-A1 Protected piperazino group-bearing organoxysilane compound and making method PIEZO1, VCL, VIM SIGMAR1 1050/4885SMN1; SMN2 1719/4885POLB 1859/4885
US-12545809-B2 Moisture-curing conformal coating compositions COL1A1, COL2A1, MSR1 SIGMAR1 42/4885SMN1; SMN2 181/4885POLB 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.