Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 9/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718689 | 0.74 | MMP2 (0.53) | MMP13MMP9MMP3MMP2ADAMTS4 | |
| SCHEMBL569561 | 0.74 | MMP9 (0.49) | MMP13MMP9MMP3MMP2ADAMTS4 | |
| SCHEMBL18019119 | 0.73 | MMP13 (0.65) | MMP13MMP9CTSKMMP3MMP2 | |
| SCHEMBL3708023 | 0.73 | MMP13 (0.45) | MMP13MMP9MMP3MMP2ADAMTS4 | |
| SCHEMBL569559 | 0.73 | CA1 (0.65) | MMP13MMP2ADAMTS4MMP1ALDH1A1 | |
| SCHEMBL28244975 | 0.72 | CTSK (0.59) | CTSK | |
| SCHEMBL569562 | 0.72 | CA12 (0.65) | MMP13MMP2ADAMTS4MMP1ALDH1A1 | |
| SCHEMBL569947 | 0.72 | CA12 (0.65) | MMP13MMP2ADAMTS4MMP1ALDH1A1 | |
| SCHEMBL5239891 | 0.72 | CNR2 (0.52) | MMP13MMP9MMP3MMP2MMP1 | |
| SCHEMBL7354064 | 0.70 | MMP9 (0.69) | MMP13MMP9MMP3MMP2ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393495-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089752-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-08-12 | — | — | WO | disclosed |