Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.53 |
| ▸ | MMP9 | P14780 | 7/20 | 0.53 |
| ▸ | MMP13 | P45452 | 9/20 | 0.48 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.45 |
| ▸ | TARS1 | P26639 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 3/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7945033 | 0.83 | MMP2 (0.58) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL1800122 | 0.81 | MMP2 (0.65) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL1800019 | 0.79 | MMP2 (0.62) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL7215717 | 0.79 | ALDH1A1 (0.47) | MMP2MMP9MMP13ADAMTS4ITGB3 | |
| SCHEMBL7215705 | 0.79 | ALDH1A1 (0.47) | MMP2MMP9MMP13ADAMTS4ITGB3 | |
| SCHEMBL5036997 | 0.78 | MMP13 (0.44) | MMP2MMP9MMP13MMP3 | |
| Hydrochloric Acid SCHEMBL6504666 | 0.78 | ALDH1A1 (0.46) | MMP2MMP9MMP13ADAMTS4ITGB3 | |
| Hydrochloric Acid SCHEMBL6495647 | 0.78 | ALDH1A1 (0.46) | MMP2MMP9MMP13ADAMTS4ITGB3 | |
| SCHEMBL13639190 | 0.78 | MMP2 (0.48) | MMP2MMP9MMP13MMP3MMP1 | |
| SCHEMBL13639186 | 0.78 | MMP2 (0.48) | MMP2MMP9MMP13MMP3MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393495-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. (IL) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010089752-A1 | CARJBAMOYLPHOSPHONATES AS INHIBITORS AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-08-12 | — | — | WO | disclosed |