Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681679 | 0.87 | TDP1 (0.42) | TTRHTR2ASLC6A4HRH1 | |
| SCHEMBL8695511 | 0.86 | SLC6A4 (0.40) | LPAR1LPAR5LTA4HHTR2ASLC6A4 | |
| SCHEMBL8405400 | 0.86 | TTR (0.47) | TTRLPAR1LPAR5LTA4HHTR2A | |
| SCHEMBL10835646 | 0.85 | SLC6A4 (0.40) | LPAR1LPAR5HTR2ASLC6A4NR3C1 | |
| SCHEMBL10877632 | 0.84 | MAOB (0.48) | HTR2ASLC6A4 | |
| SCHEMBL10877600 | 0.84 | SLC6A4 (0.47) | TSHRHTR2ASLC6A4 | |
| SCHEMBL8567112 | 0.84 | TTR (0.40) | TTRLPAR1LPAR5HRH1 | |
| SCHEMBL10876463 | 0.83 | SLC6A4 (0.40) | LPAR1LPAR5ALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10743171 | 0.83 | TTR (0.44) | TTRLPAR1LPAR5LTA4HHTR2A | |
| SCHEMBL10547891 | 0.83 | TTR (0.44) | TTRLPAR1LPAR5LTA4HHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187836-A4 | OXIME INSECTICIDES. | COMMW SCIENT IND RES ORG (AU) | 1987-12-09 | — | — | EP | claimed |
| EP-0187836-A1 | OXIME INSECTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1986-07-23 | — | — | EP | claimed |
| WO-1986000894-A1 | OXIME INSECTICIDES | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) | 1986-02-13 | — | — | WO | claimed |
| EP-0024612-B1 | NEW 4-FLUORO-3-PHENOXY-BENZYL-ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1983-10-05 | — | — | EP | claimed |
| EP-0024612-A2 | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | BAYER AG (DE) | 1981-03-11 | — | — | EP | claimed |
| EP-2154123-B1 | METHOD FOR PRODUCING BENZALDEHYDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2013-10-23 | — | — | EP | disclosed |
| WO-2010086876-A2 | ETHER SYNTHESIS | ADITYA BIRLA SCIENCE & TECHNOLOGY CO. LTD. (IN) | 2010-08-05 | — | — | WO | disclosed |
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | KUREHA CORPORATION (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1278720-B1 | 1,4-DIARYL-2-FLUORO-4-CYANO-2-BUTENES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES USEFUL THEREFOR | BASF AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| CN-1523958-A | Pesticide compositions comprising malononitrile compounds | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-08-25 | — | — | CN | disclosed |
| US-6770463-B2 | INSECTICIDES AND ACARICIDES; AROMATIC SUBSTITUTED HALOALKENES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-0024611-A1 | Process for preparing substituted benzaldehydes | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024612-A2 | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | BAYER AG (DE) | 1981-03-11 | — | — | EP | disclosed |
| EP-0024019-A1 | Process for the production of 4-fluoro-3-phenoxy-toluene | BAYER AG (DE) | 1981-02-18 | — | — | EP | disclosed |
| US-4231953-A | Fluoro substituted aryl esters and thiolesters of amino acids | ZOECON CORPORATION (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229368-A | Esters and thiolesters of unsaturated acids | ZOECON CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4225533-A | Fluorobenzyl esters of cyclopropanecarboxylic acids | ZOECON CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |
| EP-0008734-A1 | Process for the preparation of 4-fluor-3-phenoxytoluene | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
| EP-0008732-A2 | Fluorine-containing esters of phenylacetic acids, process for their preparation and their use as insecticides and acaricides; intermediate products for their preparation | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101783-A1 | N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide | HBZ, ACMSD, HDHD5 | TTR 4150/4885LPAR1 1365/4885LPAR5 604/4885 |
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | TTR 2706/4885LPAR1 1771/4885LPAR5 1884/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.