Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL27483882 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL27731212 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL5363705 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL371303 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL27710812 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL27485266 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL3712402 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL688161 | 1.00 | TSHR (0.90) | — | |
| Maleic Acid SCHEMBL10408929 | 1.00 | TSHR (0.90) | — | |
| Fumaric Acid SCHEMBL27731207 | 1.00 | TSHR (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119215700-A | Cation exchange membrane with single molecule valence selection and preparation method thereof | 孟广祯 | 2024-12-31 | — | — | CN | claimed |
| CN-119019836-A | Wear-resistant antibacterial TPE composite material and application thereof in yoga mats | 安徽观唐橡塑制品有限公司 | 2024-11-26 | — | — | CN | claimed |
| CN-117619168-A | Organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2024-03-01 | — | — | CN | claimed |
| CN-115090124-B | Preparation method and application of electric double layer composite membrane generated by interfacial polymerization reaction | 浙江理工大学 | 2023-09-05 | — | — | CN | claimed |
| CN-109734915-B | Inhibitor and preparation method and application thereof | 浙江清华柔性电子技术研究院 | 2021-07-13 | — | — | CN | claimed |
| CN-112940258-A | Reactive inhibitor and preparation method thereof, silicone rubber composition, silicone rubber and preparation method thereof | 浙江清华柔性电子技术研究院 | 2021-06-11 | — | — | CN | claimed |
| CN-107442169-B | Catalyst loaded with chlorine-containing organotin and nitrogen-containing compound and preparation method and application thereof | 太原理工大学 | 2020-02-07 | — | — | CN | claimed |
| EP-3127896-B1 | METHOD FOR PREPARING IMINODISUCCINATE CHELATING AGENT | HEBEI THINK DO ENV CO LTD (CN) | 2019-06-05 | — | — | EP | claimed |
| US-20190055337-A1 | LOW-COST SYNTHESIS OF MACROMONOMERS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2019-02-21 | — | — | US | claimed |
| CN-109069496-A | For treating the arimoclomol of glucocerebrosidase related disease | 奥菲泽米有限公司 | 2018-12-21 | — | — | CN | claimed |
| EP-2999723-B1 | CATIONIC POLYMERIZATION PROCESS FOR THE SYNTHESIS OF NANO-STRUCTURED POLYMERS CONTAINING GRAPHENE | VERSALIS SPA (IT) | 2018-10-17 | — | — | EP | claimed |
| WO-2017186919-A1 | ARIMOCLOMOL FOR TREATING GLUCOCEREBROSIDASE ASSOCIATED DISORDERS | ORPHAZYME APS (DK) | 2017-11-02 | — | — | WO | claimed |
| WO-2017136565-A1 | LOW-COST SYNTHESIS OF MACROMONOMERS | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2017-08-10 | — | — | WO | claimed |
| CN-106479700-A | A kind of semiconductor silicon material lapping liquid abluent and preparation method thereof | 佛山迅拓奥科技有限公司 | 2017-03-08 | — | — | CN | claimed |
| US-9493594-B2 | Cationic polymerization process for the synthesis of nano-structured polymers containing graphene | VERSALIS S.P.A. (IT) | 2016-11-15 | — | — | US | claimed |
| US-20160152748-A1 | Cationic Polymerization Process For The Synthesis Of Nano-Structured Polymers Containing Graphene | VERSALIS SPA (IT) | 2016-06-02 | — | — | US | claimed |
| EP-2999723-A1 | CATIONIC POLYMERIZATION PROCESS FOR THE SYNTHESIS OF NANO-STRUCTURED POLYMERS CONTAINING GRAPHENE | Versalis S.p.A (IT) | 2016-03-30 | — | — | EP | claimed |
| US-20070072910-A1 | Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans | NEXGEN PHARMA, INC. | 2007-03-29 | — | — | US | claimed |
| EP-1114003-B1 | PORE-FORMING PARTICLES FOR CONCRETE AND MORTAR, METHOD FOR THE PRODUCTION THEREOF AND CEMENT MORTAR CONTAINING SAID PARTICLES | HEIDELBERGER BAUCHEMIE GMBH (DE) | 2002-06-19 | — | — | EP | claimed |
| US-6159965-A | Anti-emetic pharmaceutical compositions containing methotrimeprazine | LINK PHARMACEUTICALS LIMITED (GB) | 2000-12-12 | — | — | US | claimed |