Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | MOK | Q9UQ07 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188618 | 0.91 | MMP2 (0.47) | ALDH1A1MMP2MMP8MMP13 | |
| SCHEMBL3721263 | 0.81 | TACR2 (0.42) | ACP1MOKALDH1A1MMP2MMP8 | |
| SCHEMBL3713979 | 0.76 | GRM2 (0.51) | ACP1MOKALDH1A1 | |
| SCHEMBL255145 | 0.74 | MMP13 (0.57) | ALDH1A1MMP2MMP8MMP13 | |
| SCHEMBL14715273 | 0.72 | MMP13 (0.56) | ALDH1A1MMP2MMP8MMP13HRH3 | |
| SCHEMBL3709419 | 0.71 | PARP1 (0.45) | MMP2MMP8MMP13HRH3 | |
| SCHEMBL26096917 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MMP2MMP8MMP13 | |
| SCHEMBL10749116 | 0.71 | SCN9A (0.57) | — | |
| SCHEMBL3721164 | 0.71 | PARP1 (0.47) | MOKMMP2MMP8MMP13HRH3 | |
| SCHEMBL3712338 | 0.71 | MMP2 (0.51) | MMP2MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |