Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 3/20 | 0.51 |
| ▸ | MOK | Q9UQ07 | 7/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13188262 | 0.94 | GRM2 (0.55) | GRM2ACP1MOKPDE10AJAK2 | |
| SCHEMBL13188454 | 0.81 | GRM2 (0.56) | GRM2ACP1MOKPDE10AKDM4E | |
| SCHEMBL3713943 | 0.80 | MAPK1 (0.45) | ACP1 | |
| SCHEMBL3713515 | 0.79 | MAPK1 (0.47) | ALDH1A1 | |
| SCHEMBL3715035 | 0.79 | SMN1; SMN2 (0.47) | LMNA | |
| SCHEMBL3715918 | 0.79 | MAPK1 (0.45) | ACP1JAK2 | |
| SCHEMBL3720699 | 0.78 | MAPK1 (0.47) | — | |
| SCHEMBL3717015 | 0.76 | ACP1 (0.42) | ACP1MOK | |
| SCHEMBL3711281 | 0.76 | ABL1 (0.45) | ACP1JAK2JAK3 | |
| SCHEMBL3713277 | 0.76 | ACP1 (0.44) | ACP1MOKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |