Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 10/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 5/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313016 | 0.78 | CA12 (0.54) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL9313011 | 0.78 | CA12 (0.54) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL13479598 | 0.78 | RRM1 (0.64) | RRM1KMT2AMEN1GAAMAPT | |
| SCHEMBL15347364 | 0.78 | RRM1 (0.64) | RRM1KMT2AMEN1GAAMAPT | |
| SCHEMBL23761140 | 0.77 | KMT2A (0.87) | RRM1KMT2AMEN1GAAMAPT | |
| SCHEMBL13840419 | 0.74 | KMT2A (0.71) | RRM1KMT2AMEN1GAAMAPT | |
| SCHEMBL22624834 | 0.74 | MAPT (0.70) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL17395842 | 0.73 | MAPT (0.65) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL17395843 | 0.73 | MAPT (0.65) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL18963233 | 0.73 | RRM1 (0.71) | RRM1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | claimed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | claimed |
| US-8791299-B2 | Compounds for the inhibition of herpes viruses | UNIVERSITE LAVAL (CA) | 2014-07-29 | — | — | US | disclosed |
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | UNIVERSITE LAVAL (CA) | 2012-06-21 | — | — | US | disclosed |
| WO-2010132992-A1 | COMPOUNDS FOR THE INHIBITION OF HERPESVIRUSES | UNIVERSITé LAVAL (CA) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157538-A1 | Compounds for the Inhibition of Herpes Viruses | NOS3, NOS1, DNA2 | RRM1 2179/4885KMT2A 523/4885MEN1 1837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.