Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713458 | 0.88 | GRM5 (0.45) | TSHRTDP1L3MBTL1MAPTIGF1R | |
| SCHEMBL3713446 | 0.88 | ALDH1A1 (0.47) | TSHRTDP1L3MBTL1MAPTIGF1R | |
| SCHEMBL13188762 | 0.84 | KCNH3 (0.44) | KCNH3MAPTHTTALDH1A1KDM4E | |
| SCHEMBL3714672 | 0.83 | KMT2A (0.44) | TSHRL3MBTL1MAPTHTTALDH1A1 | |
| SCHEMBL3713336 | 0.80 | ESR1 (0.41) | KCNH3TSHRTDP1L3MBTL1MAPT | |
| SCHEMBL3713958 | 0.79 | L3MBTL1 (0.42) | TSHRL3MBTL1MAPTIGF1RP2RY12 | |
| SCHEMBL3710210 | 0.79 | ESR1 (0.41) | KCNH3TSHRTDP1L3MBTL1MAPT | |
| SCHEMBL3713822 | 0.71 | TSHR (0.54) | TSHRTDP1L3MBTL1MAPTIGF1R | |
| SCHEMBL13188432 | 0.71 | GRM5 (0.52) | L3MBTL1SMN1; SMN2ACACBNPC1RAB9A | |
| SCHEMBL3712789 | 0.70 | TSHR (0.50) | TSHRTDP1L3MBTL1MAPTIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010100475-A1 | HYDROXAMIC ACID DERIVATIVES AS GRAM-NEGATIVE ANTIBACTERIAL AGENTS | ASTRAZENECA AB (SE) | 2010-09-10 | — | — | WO | disclosed |