Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17646302 | 0.81 | MAPT (0.39) | TSHRCA1CA2POLBMAPT | |
| SCHEMBL20369021 | 0.74 | POLB (0.44) | CA1CA2CA9POLB | |
| SCHEMBL28341050 | 0.72 | CES2 (0.33) | CA9 | |
| Bicarbonate SCHEMBL28481344 | 0.70 | TSHR (0.39) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL2089158 | 0.69 | CA1 (0.36) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL7276616 | 0.69 | AGBL2 (0.33) | — | |
| SCHEMBL8827274 | 0.69 | POLB (0.39) | POLB | |
| SCHEMBL20127258 | 0.67 | TSHR (0.33) | TSHRSMN1; SMN2CA1CA2CA9 | |
| SCHEMBL5540730 | 0.64 | SOD1 (0.47) | — | |
| SCHEMBL99544 | 0.64 | DAO (0.43) | CA1CA2CA9TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215676-A | Specific conjugation of antibody drug conjugates | 杭州多禧生物科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| CN-117980327-A | Specific coupling of antibodies | 杭州多禧生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116143678-A | Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof | 杭州多禧生物科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-02-23 | — | — | US | claimed |
| CN-115443134-A | Conjugates of cell binding molecules and camptothecin analogs | 杭州多禧生物科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-115300640-A | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-11-08 | — | — | CN | claimed |
| CN-108289964-B | Novel linkers and their use for specific coupling of drugs and biomolecules | 杭州多禧生物科技有限公司 | 2022-08-12 | — | — | CN | claimed |
| EP-3888691-A1 | CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LIKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS | Hangzhou Dac Biotech Co., Ltd. (CN) | 2021-10-06 | — | — | EP | claimed |
| CN-113350518-A | Conjugated bridge linkers to cell binding molecules | 杭州多禧生物科技有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-113195487-A | 2, 3-diaminosuccinyl conjugate linkers | 杭州多禧生物科技有限公司 | 2021-07-30 | — | — | CN | claimed |
| WO-2018185526-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2018-10-11 | — | — | WO | claimed |
| EP-3319936-A2 | BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES | Suzhou M-conj Biotech Co., Ltd. (CN) | 2018-05-16 | — | — | EP | claimed |
| US-20170209595-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-07-27 | — | — | US | claimed |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD. (CN) | 2017-06-22 | — | — | US | claimed |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | SUZHOU M-CONJ BIOTECH CO., LTD (CN) | 2015-11-05 | — | — | US | claimed |
| EP-1165581-B1 | METHOD FOR THE PRODUCTION OF 4'-DEMETHYL - 4'-PHOSPHATE-2\",3\" - BIS PENTAFLUOROPHENOXYACETYL - 4\",6\"-ETHYLIDENE - BETA-D- GLUCOSIDE EPIPODOPHYLLOTOXIN AND THE SALTS THEREOF | PF MEDICAMENT (FR) | 2003-01-15 | — | — | EP | claimed |
| US-6107284-A | Water-soluble derivatives of epipodophyllotoxin, process for their preparation, their use as medicinal products and their intended use in anti-cancer treatments | PIERRE FABRE MEDICAMENT (FR) | 2000-08-22 | — | — | US | claimed |
| EP-0787135-B1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PF MEDICAMENT (FR) | 2000-05-24 | — | — | EP | claimed |
| EP-0787135-A1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1997-08-06 | — | — | EP | claimed |
| WO-1996012727-A1 | WATER-SOLUBLE EPIPODOPHYLLOTOXIN DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF AS A DRUG AND FOR TREATING CANCER | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230057350-A1 | A CONJUGATE OF AN AMANITA TOXIN WITH BRANCHED LINKERS | BTN3A1, ANTXR2, CLTA | TSHR 863/4885SMN1; SMN2 3761/4885CA1 670/4885 |
| US-20170173176-A1 | ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE | AADAC, EPCAM, DCLRE1A | TSHR 2628/4885SMN1; SMN2 4722/4885CA1 412/4885 |
| US-20170209595-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | TSHR 1781/4885SMN1; SMN2 3882/4885CA1 249/4885 |
| US-20150314017-A1 | DISULFUR BRIDGE LINKERS FOR CONJUGATION OF A CELL-BINDING MOLECULE | CD74, CD2, EPCAM | TSHR 1781/4885SMN1; SMN2 3882/4885CA1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.