Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5165664 | 0.87 | CYP3A4 (0.41) | CYP3A4PPARDALDH1A1TSHR | |
| SCHEMBL1632695 | 0.84 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL3815405 | 0.79 | CYP3A4 (0.46) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL3424891 | 0.77 | CYP3A4 (0.34) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL20503103 | 0.77 | ALDH1A1 (0.61) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL22772619 | 0.77 | CYP3A4 (0.34) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL3429790 | 0.77 | CYP3A4 (0.34) | CYP3A4ALDH1A1TSHR | |
| SCHEMBL632894 | 0.77 | ALDH1A1 (0.50) | CYP3A4PPARDALDH1A1TSHR | |
| SCHEMBL10225642 | 0.76 | CYP3A4 (0.33) | CYP3A4ALDH1A1 | |
| SCHEMBL3817581 | 0.76 | CYP3A4 (0.67) | CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050259-A | Silicon-phosphorus block intrinsic flame-retardant polyurea material and preparation method thereof | 北京化工大学 | 2023-11-14 | — | — | CN | claimed |
| CN-117050259-A | Silicon-phosphorus block intrinsic flame-retardant polyurea material and preparation method thereof | 北京化工大学 | 2023-11-14 | — | — | CN | disclosed |
| WO-2016184878-A1 | AQUEOUS INKJET INKS | AGFA-GEVAERT (BE) | 2016-11-24 | — | — | WO | disclosed |
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-12-16 | — | — | US | disclosed |
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-12-16 | — | — | US | disclosed |
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB | 2010-12-16 | — | — | US | disclosed |
| WO-2010142978-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | WO | disclosed |
| WO-2010142978-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | WO | disclosed |
| US-6930100-B2 | Phosphate prodrugs of fluoroxindoles | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-08-16 | — | — | US | disclosed |
| US-20030195169-A1 | Phosphate prodrugs of fluorooxindoles | BRISTOL-MYERS SQUIBB COMPANY | 2003-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317624-A1 | HETEROCYCLIC UREA DERIVATIVES AND METHODS OF USE THEREOF | UROD, UMPS, SLC14A1 | CYP3A4 62/4885PPARD 1169/4885ALDH1A1 847/4885 |
| US-20030195169-A1 | Phosphate prodrugs of fluorooxindoles | KCNA5, KCNN3, CACNA1E | CYP3A4 525/4885PPARD 3667/4885ALDH1A1 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.