Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726439 | 0.80 | ACACB (0.39) | RAB9AACACBKDM4EMAPTPARG | |
| SCHEMBL3716940 | 0.76 | ACACB (0.42) | SMN1; SMN2ACACBMAPTPARG | |
| SCHEMBL3726994 | 0.72 | ACACB (0.42) | SMN1; SMN2ACACBKDM4EMAPTPARG | |
| SCHEMBL3723076 | 0.67 | MTNR1A (0.50) | SMN1; SMN2ACACBMAPT | |
| SCHEMBL3726992 | 0.67 | ESRRA (0.53) | SMN1; SMN2ACACBKDM4EMAPTPARG | |
| SCHEMBL9503543 | 0.67 | MAPT (0.49) | SMN1; SMN2ACACBMAPT | |
| SCHEMBL3720106 | 0.66 | SMN1; SMN2 (0.49) | SMN1; SMN2ACACBKDM4E | |
| SCHEMBL3720624 | 0.66 | ALDH1A1 (0.49) | RAB9ASMN1; SMN2ACACB | |
| SCHEMBL1390808 | 0.66 | RAB9A (0.41) | RAB9ASMN1; SMN2ACACBKDM4EMAPT | |
| SCHEMBL3718635 | 0.65 | PPARA (0.45) | RAB9ASMN1; SMN2ACACBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | claimed |
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |