Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284141 | 0.82 | APLNR (0.55) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL2926580 | 0.81 | TSHR (0.37) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL11525177 | 0.77 | MEN1 (0.56) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL24514107 | 0.75 | APLNR (0.50) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL4756453 | 0.75 | APLNR (0.51) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL18102802 | 0.75 | TDP1 (0.59) | GAAMEN1KMT2AMAPK1LMNA | |
| SCHEMBL12318662 | 0.75 | TDP1 (0.51) | GAAMEN1KMT2AMAPK1TSHR | |
| SCHEMBL18756274 | 0.75 | SMN1; SMN2 (0.46) | APLNRGAAMEN1KMT2AMAPK1 | |
| SCHEMBL25369963 | 0.74 | TSHR (0.53) | MAPK1LMNATSHRTDP1ALDH1A1 | |
| SCHEMBL27922850 | 0.73 | APLNR (0.42) | APLNRGAAMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109821-A1 | SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | UNIV MCMASTER (CA) | 2026-04-23 | — | — | US | disclosed |
| US-12359026-B2 | In situ gelling zwitterionic hydrogel compositions, and methods of use thereof | MCMASTER UNIVERSITY (CA) | 2025-07-15 | — | — | US | disclosed |
| CN-119838022-A | Amatoxin conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2025-04-18 | — | — | CN | disclosed |
| CN-113423430-B | Amatoxin conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| US-20230220166-A1 | IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | MCMASTER UNIVERSITY (CA) | 2023-07-13 | — | — | US | disclosed |
| EP-4153664-A1 | IN SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | McMaster University (CA) | 2023-03-29 | — | — | EP | disclosed |
| CN-115475249-A | Photoresponse carbon monoxide release nanogel and preparation method and application thereof | 西北工业大学 | 2022-12-16 | — | — | CN | disclosed |
| CN-113423430-A | Amanitoxin conjugates containing branched linkers | 杭州多禧生物科技有限公司 | 2021-09-21 | — | — | CN | disclosed |
| US-20200256860-A1 | PRINTABLE HYDROGELS FOR BIOMOLECULE IMMOBILIZATION AND STABILIZATION | MCMASTER UNIVERSITY (CA) | 2020-08-13 | — | — | US | disclosed |
| US-20190321512-A1 | POLY(OLIGOETHYLENE GLYCOL METHACRYLATE) HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | MCMASTER UNIVERSITY (CA) | 2019-10-24 | — | — | US | disclosed |
| WO-2010098495-A1 | IMIDAZOLYLPYRAZINE DERIVATIVES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-09-02 | — | — | WO | disclosed |
| EP-2181992-A1 | POLYCYCLIC COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2010-05-05 | — | — | EP | disclosed |
| WO-2010025197-A1 | PROCESS FOR PREPARING CERTAIN CINNAMIDE COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-04 | — | — | WO | disclosed |
| US-20090062529-A1 | MULTI-CYCLIC COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD., (JP) | 2009-03-05 | — | — | US | disclosed |
| US-20090062529-A1 | MULTI-CYCLIC COMPOUNDS | EISAI R&D MANAGEMENT CO., LTD., (JP) | 2009-03-05 | — | — | US | disclosed |
| US-4451568-A | PHOTOPOLYMERIZATION OF A MIXTURE OF ACRYLIC ACID, AMINO ACRYLATE ADHESION PROMOTER AND AN ACRYLATE ABLE TO BIND BIOSUBSTANCES | BATTELLE MEMORIAL INSTITUTE (CH) | 1984-05-29 | — | — | US | disclosed |
| WO-1981001412-A1 | ADHESIVE COMPOSITION FOR FIXING BIOFUNCTIONAL MOLECULES | BATTELLE MEMORIAL INSTITUTE (CH) | 1981-05-28 | — | — | WO | disclosed |
| EP-0029411-A1 | Adhesive composition for depositing an adhesive coating able to fix biofunctional molecules, coating obtained and process for its preparation, substrate covered with the coating and its use as a biocatalyst | BATTELLE MEMORIAL INSTITUTE (CH) | 1981-05-27 | — | — | EP | disclosed |
| US-4087487-A | THREE-DIMENSIONAL DIAZOTIZABLE POLYMER WITH LINEAR POLYMER HAVING BINDING LIGANDS | CESKOSLOVENSKA AKADEMIE VED (CS) | 1978-05-02 | — | — | US | disclosed |
| US-3969436-A | Carriers for biologically active compounds and methods for the production thereof | CESKOSLOVENSKA AKADEMIE VED (CS) | 1976-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109821-A1 | SITU GELLING ZWITTERIONIC HYDROGEL COMPOSITIONS, AND METHODS OF USE THEREOF | ITGA1, ITGB1, F12 | APLNR 3991/4885GAA 4814/4885MEN1 3352/4885 |
| US-20090062529-A1 | MULTI-CYCLIC COMPOUNDS | APP, BACE1, PSEN1 | APLNR 2385/4885GAA 1552/4885MEN1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.