Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 9/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 5/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794470 | 0.89 | RORC (0.33) | RORCINSRIGF1RFFAR1MAPT | |
| SCHEMBL1708103 | 0.86 | FFAR1 (0.39) | CD274PDCD1FFAR1 | |
| SCHEMBL1708294 | 0.85 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL1708101 | 0.85 | RORC (0.33) | CD274PDCD1RORCEEDSUZ12 | |
| SCHEMBL1707921 | 0.84 | CD274 (0.34) | CD274PDCD1INSRIGF1RFFAR1 | |
| SCHEMBL1708447 | 0.83 | CD274 (0.33) | CD274PDCD1INSRIGF1RFFAR1 | |
| SCHEMBL3798510 | 0.81 | ALDH1A1 (0.33) | RORCFFAR1MAPTALDH1A1 | |
| SCHEMBL1708348 | 0.79 | GAA (0.39) | CD274MAPTALDH1A1LMNAGAA | |
| SCHEMBL1708220 | 0.78 | INSR (0.35) | CD274PDCD1INSRIGF1RFFAR1 | |
| SCHEMBL3717530 | 0.78 | FFAR1 (0.35) | CD274PDCD1INSRIGF1RFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440541-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-04-18 | — | — | EP | disclosed |
| WO-2010143733-A1 | NOVEL FUSED CYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-12-16 | — | — | WO | disclosed |