Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL3717971 | 0.90 | ALDH1A1 (0.54) | ALDH1A1CYP3A4TSHRCES2CES1 | |
| SCHEMBL5038514 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL2376145 | 0.84 | PTGS2 (0.41) | ALDH1A1CYP3A4MAPTHPGDTSHR | |
| SCHEMBL8060532 | 0.84 | TAS1R3 (0.49) | ALDH1A1TSHRTAS1R3TAS1R1 | |
| SCHEMBL472890 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4MAPTHPGDTSHR | |
| SCHEMBL14958 | 0.80 | MAOA (0.52) | ALDH1A1MAPTCES2CES1MAOA | |
| SCHEMBL7560324 | 0.79 | MAOA (0.41) | ALDH1A1MAPTCES2CES1MAOA | |
| Styrene SCHEMBL9583045 | 0.78 | ALDH1A1 (0.70) | ALDH1A1CYP3A4MAPTHPGDTSHR | |
| SCHEMBL5704306 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1KMT2ANPC1 | |
| Styrene SCHEMBL1974109 | 0.78 | ALDH1A1 (0.70) | ALDH1A1CYP3A4MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2011510134-A | — | — | 2011-03-31 | — | — | JP | claimed |
| EP-2238201-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | Nova Chemicals (International) S.A. (CH) | 2010-10-13 | — | — | EP | claimed |
| WO-2009091454-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) | 2009-07-23 | — | — | WO | claimed |
| US-20090181253-A1 | PARTICULATE INTERPENETRATING NETWORK POLYMER | NOVA CHEMICALS INC. (US) | 2009-07-16 | — | — | US | claimed |
| US-4788253-A | ELASTOMER WITH GRAFTED SHELL IN MATRIX, WEATHER RESISTANCE | BASF AKTIENGESELLSCHAFT (DE) | 1988-11-29 | — | — | US | claimed |
| EP-3350262-A1 | STYRENIC BLOCK COPOLYMER COMPOSITIONS | Kraton Polymers U.S. LLC (US) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017049235-A1 | STYRENIC BLOCK COPOLYMER COMPOSITIONS | KRATON POLYMERS U.S. LLC (US) | 2017-03-23 | — | — | WO | disclosed |