Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.43 |
| ▸ | AR | P10275 | 14/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720603 | 0.80 | MRGPRX1 (0.42) | SLC22A12ARLTA4HPTGS2P2RY1 | |
| SCHEMBL3721302 | 0.79 | AR (0.44) | SLC22A12ARLTA4HPTGS2 | |
| SCHEMBL3718903 | 0.76 | LTA4H (0.41) | SLC22A12ARLTA4HPTGS2P2RY1 | |
| SCHEMBL3722454 | 0.75 | P2RY1 (0.39) | ARLTA4HPTGS2P2RY1 | |
| SCHEMBL3720604 | 0.74 | P2RY1 (0.45) | LTA4HPTGS2P2RY1 | |
| SCHEMBL1933633 | 0.73 | AR (0.50) | SLC22A12ARLTA4HPTGS2 | |
| SCHEMBL2132630 | 0.73 | ALDH1A1 (0.40) | AR | |
| SCHEMBL3722554 | 0.73 | P2RY1 (0.39) | SLC22A12ARLTA4HPTGS2P2RY1 | |
| SCHEMBL8344932 | 0.72 | HTR1A (0.47) | SLC22A12ARP2RY1 | |
| SCHEMBL18615346 | 0.72 | KMT2A (0.43) | SLC22A12ARERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097373-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |