Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 9/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7220250 | 0.73 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3P2RY1 | |
| SCHEMBL4008471 | 0.73 | HTR1A (0.55) | HTR1ASLC6A2SLC6A4SLC6A3P2RY1 | |
| SCHEMBL3718259 | 0.72 | SLC22A12 (0.43) | P2RY1ARSLC22A12 | |
| SCHEMBL909452 | 0.72 | PLCG1 (0.51) | ARPLCG1 | |
| SCHEMBL3721302 | 0.72 | AR (0.44) | HTR1ASLC6A2SLC6A4SLC6A3MRGPRX1 | |
| SCHEMBL17508501 | 0.72 | TRPA1 (0.59) | HTR1ASLC6A2SLC6A4SLC6A3P2RY1 | |
| SCHEMBL18469 | 0.71 | CTSS (0.42) | HTR1ASLC6A2SLC6A4SLC6A3P2RY1 | |
| Hydrochloric Acid SCHEMBL8725899 | 0.71 | P2RY1 (0.48) | HTR1ASLC6A2SLC6A4SLC6A3P2RY1 | |
| SCHEMBL1933633 | 0.71 | AR (0.50) | ARSLC22A12 | |
| SCHEMBL8340706 | 0.71 | P2RY1 (0.52) | P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939359-A | Herbicidal pyrazine derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| EP-0773934-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003391-A1 | HERBICIDAL PYRAZINE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |