Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 4/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 8/20 | 0.38 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3721626 | 0.86 | ACACB (0.44) | — | |
| SCHEMBL3722359 | 0.86 | ALOX5 (0.42) | PDE4BALOX5PDE2ASCN9A | |
| SCHEMBL3721630 | 0.82 | MTNR1A (0.47) | ALOX5PDE2ASCN9AALDH1A1LMNA | |
| SCHEMBL3722365 | 0.82 | ALOX5 (0.38) | ALOX5PDE2ASCN9A | |
| SCHEMBL3724294 | 0.77 | PDE4B (0.55) | PDE4BSCN9ASCN7AKCNH2ALDH1A1 | |
| SCHEMBL3721431 | 0.76 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2ALDH1A1 | |
| SCHEMBL3722547 | 0.75 | PDE4B (0.52) | PDE4BALOX5SCN9ASCN7AKCNH2 | |
| SCHEMBL3719669 | 0.75 | PDE4B (0.49) | PDE4BALOX5SCN9ASCN7AKCNH2 | |
| SCHEMBL3719934 | 0.75 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2 | |
| SCHEMBL3719578 | 0.75 | PDE4B (0.53) | PDE4BSCN9ASCN7AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |